Modification of PLA Scaffold Surface for Medical Applications
Materials used for medical applications (e.g., the cellular scaffold) should have not only the specific chemical composition, but the surface layer properties as well. For this reason, a method which enables an increase in the number of pores, wettability of the surface, and improvement the conditio...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-02-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/11/4/1815 |
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| author | Michał Młotek Agnieszka Gadomska-Gajadhur Aleksandra Sobczak Aleksandra Kruk Michalina Perron Krzysztof Krawczyk |
| author_facet | Michał Młotek Agnieszka Gadomska-Gajadhur Aleksandra Sobczak Aleksandra Kruk Michalina Perron Krzysztof Krawczyk |
| author_sort | Michał Młotek |
| collection | DOAJ |
| description | Materials used for medical applications (e.g., the cellular scaffold) should have not only the specific chemical composition, but the surface layer properties as well. For this reason, a method which enables an increase in the number of pores, wettability of the surface, and improvement the conditions of nutrient transportation into the membrane is being studied. The plasma of a dielectric barrier discharge was applied for the surface modification of polylactide obtained by dry or wet phase inversion. The plasma-modified surface was analyzed by contact angle measurements with water and diiodomethane. The surface free energy (SFE) was calculated by the Owens–Wendt method. The highest SFE and its polar component (67.6 mJ/m<sup>2</sup> and 39.5 mJ/m<sup>2</sup>, respectively) were received when the process was conducted in an Ar + CO<sub>2</sub> gas mixture with a discharge power of 20 W. The purpose of this research was to increase the wettability and porosity of the membrane’s surface. It can be concluded that the dielectric barrier discharge can effectively change the surface of the polylactide membranes, and that the structure of the modified membranes was not damaged during modification. The process of modification was easier for the membranes made by dry phase inversion. These materials had higher SFE values after the modification. |
| first_indexed | 2024-03-09T00:45:56Z |
| format | Article |
| id | doaj.art-b17e8134bdcb4351b575e9b690c4ee02 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-09T00:45:56Z |
| publishDate | 2021-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-b17e8134bdcb4351b575e9b690c4ee022023-12-11T17:30:26ZengMDPI AGApplied Sciences2076-34172021-02-01114181510.3390/app11041815Modification of PLA Scaffold Surface for Medical ApplicationsMichał Młotek0Agnieszka Gadomska-Gajadhur1Aleksandra Sobczak2Aleksandra Kruk3Michalina Perron4Krzysztof Krawczyk5Faculty of Chemistry, Warsaw University of Technology, 0-664 Warszawa, PolandFaculty of Chemistry, Warsaw University of Technology, 0-664 Warszawa, PolandFaculty of Chemistry, Warsaw University of Technology, 0-664 Warszawa, PolandFaculty of Chemistry, Warsaw University of Technology, 0-664 Warszawa, PolandFaculty of Chemistry, Warsaw University of Technology, 0-664 Warszawa, PolandFaculty of Chemistry, Warsaw University of Technology, 0-664 Warszawa, PolandMaterials used for medical applications (e.g., the cellular scaffold) should have not only the specific chemical composition, but the surface layer properties as well. For this reason, a method which enables an increase in the number of pores, wettability of the surface, and improvement the conditions of nutrient transportation into the membrane is being studied. The plasma of a dielectric barrier discharge was applied for the surface modification of polylactide obtained by dry or wet phase inversion. The plasma-modified surface was analyzed by contact angle measurements with water and diiodomethane. The surface free energy (SFE) was calculated by the Owens–Wendt method. The highest SFE and its polar component (67.6 mJ/m<sup>2</sup> and 39.5 mJ/m<sup>2</sup>, respectively) were received when the process was conducted in an Ar + CO<sub>2</sub> gas mixture with a discharge power of 20 W. The purpose of this research was to increase the wettability and porosity of the membrane’s surface. It can be concluded that the dielectric barrier discharge can effectively change the surface of the polylactide membranes, and that the structure of the modified membranes was not damaged during modification. The process of modification was easier for the membranes made by dry phase inversion. These materials had higher SFE values after the modification.https://www.mdpi.com/2076-3417/11/4/1815polylactidescaffolddielectric barrier discharge plasmaplasma modification |
| spellingShingle | Michał Młotek Agnieszka Gadomska-Gajadhur Aleksandra Sobczak Aleksandra Kruk Michalina Perron Krzysztof Krawczyk Modification of PLA Scaffold Surface for Medical Applications Applied Sciences polylactide scaffold dielectric barrier discharge plasma plasma modification |
| title | Modification of PLA Scaffold Surface for Medical Applications |
| title_full | Modification of PLA Scaffold Surface for Medical Applications |
| title_fullStr | Modification of PLA Scaffold Surface for Medical Applications |
| title_full_unstemmed | Modification of PLA Scaffold Surface for Medical Applications |
| title_short | Modification of PLA Scaffold Surface for Medical Applications |
| title_sort | modification of pla scaffold surface for medical applications |
| topic | polylactide scaffold dielectric barrier discharge plasma plasma modification |
| url | https://www.mdpi.com/2076-3417/11/4/1815 |
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