Comparison of analgesic efficacy of different local anesthetic volumes for erector spinae plane block in thoracotomy patients; a prospective randomized trial

Abstract Background Erector spinae plane block (ESPB) is a thoracic wall block that has been used frequently in recent years. It was aimed to compare the analgesic efficacy of bupivacaine in different volumes for ESPB in patients undergoing thoracotomy. Methods Patients who were in the age range of...

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Main Authors: Musa Zengin, Hilal Sazak, Ramazan Baldemir, Gulay Ulger, Dilara Arican, Oya Kaybal, Ali Alagoz
Format: Article
Language:English
Published: BMC 2023-02-01
Series:BMC Anesthesiology
Subjects:
Online Access:https://doi.org/10.1186/s12871-023-02004-4
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author Musa Zengin
Hilal Sazak
Ramazan Baldemir
Gulay Ulger
Dilara Arican
Oya Kaybal
Ali Alagoz
author_facet Musa Zengin
Hilal Sazak
Ramazan Baldemir
Gulay Ulger
Dilara Arican
Oya Kaybal
Ali Alagoz
author_sort Musa Zengin
collection DOAJ
description Abstract Background Erector spinae plane block (ESPB) is a thoracic wall block that has been used frequently in recent years. It was aimed to compare the analgesic efficacy of bupivacaine in different volumes for ESPB in patients undergoing thoracotomy. Methods Patients who were in the age range of 18 to 65 years, ASA I–III, had a body mass index (BMI) of 18–30 kg/m2 and were undergoing thoracotomy were included in the study. Patients were assigned to ESPB with 30 ml 0.25% bupivacaine (Group-1) or ESPB with 20 ml 0.25% bupivacaine (Group-2) groups according to the analgesia protocol. In the postoperative care unit, intravenous morphine was administered via a patient-controlled analgesia pump for 24 h. A paracetamol dose of 1 g every 8 h and a dexketoprofen dose of 50 mg twice daily were administered iv for multimodal analgesia. Results Visual analog scale (VAS) resting scores, the 1st (p = 0.001), 2nd (< 0.001), 4th (< 0.001), 8th (< 0.001), 16th (< 0.010), 24th (< 0.044), and 48th (< 0.005)-hour VAS resting results were found to be statistically significantly higher in the 20 ml group than the 30 ml group. VAS cough scores were statistically significantly higher in the 20 ml group at the 1st (< 0.003), 2nd (< 0.001), 4th (< 0.001), 8th (< 0.001), 16th (< 0.004), 24th (< 0.031), and 48th (< 0.009)-hour. Morphine consumption, and additional analgesic use were found to be statistically significantly higher in the 20 ml group than in the 30 ml group (p < 0.001, p = 0.001, respectively). There was no statistically significant difference between the groups in terms of side effects (p > 0.05). Conclusions The results of ESPB applied with 20 ml and 30 ml of local anesthetic before the surgical incision in thoracotomy patients showed that the use of 30 ml of local anesthetic provided more effective analgesia. In addition, similar side-effect rates show that 30 ml of local anesthetic can be used safely.
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spelling doaj.art-b17fea234acf404784499fe78bb8ee402023-03-22T12:12:17ZengBMCBMC Anesthesiology1471-22532023-02-012311910.1186/s12871-023-02004-4Comparison of analgesic efficacy of different local anesthetic volumes for erector spinae plane block in thoracotomy patients; a prospective randomized trialMusa Zengin0Hilal Sazak1Ramazan Baldemir2Gulay Ulger3Dilara Arican4Oya Kaybal5Ali Alagoz6University of Health Sciences, Ankara Atatürk Sanatorium Training and Research Hospital, Anesthesiology and Reanimation ClinicUniversity of Health Sciences, Ankara Atatürk Sanatorium Training and Research Hospital, Anesthesiology and Reanimation ClinicUniversity of Health Sciences, Ankara Atatürk Sanatorium Training and Research Hospital, Anesthesiology and Reanimation ClinicUniversity of Health Sciences, Ankara Atatürk Sanatorium Training and Research Hospital, Anesthesiology and Reanimation ClinicUniversity of Health Sciences, Ankara Atatürk Sanatorium Training and Research Hospital, Anesthesiology and Reanimation ClinicUniversity of Health Sciences, Ankara Atatürk Sanatorium Training and Research Hospital, Anesthesiology and Reanimation ClinicUniversity of Health Sciences, Ankara Atatürk Sanatorium Training and Research Hospital, Anesthesiology and Reanimation ClinicAbstract Background Erector spinae plane block (ESPB) is a thoracic wall block that has been used frequently in recent years. It was aimed to compare the analgesic efficacy of bupivacaine in different volumes for ESPB in patients undergoing thoracotomy. Methods Patients who were in the age range of 18 to 65 years, ASA I–III, had a body mass index (BMI) of 18–30 kg/m2 and were undergoing thoracotomy were included in the study. Patients were assigned to ESPB with 30 ml 0.25% bupivacaine (Group-1) or ESPB with 20 ml 0.25% bupivacaine (Group-2) groups according to the analgesia protocol. In the postoperative care unit, intravenous morphine was administered via a patient-controlled analgesia pump for 24 h. A paracetamol dose of 1 g every 8 h and a dexketoprofen dose of 50 mg twice daily were administered iv for multimodal analgesia. Results Visual analog scale (VAS) resting scores, the 1st (p = 0.001), 2nd (< 0.001), 4th (< 0.001), 8th (< 0.001), 16th (< 0.010), 24th (< 0.044), and 48th (< 0.005)-hour VAS resting results were found to be statistically significantly higher in the 20 ml group than the 30 ml group. VAS cough scores were statistically significantly higher in the 20 ml group at the 1st (< 0.003), 2nd (< 0.001), 4th (< 0.001), 8th (< 0.001), 16th (< 0.004), 24th (< 0.031), and 48th (< 0.009)-hour. Morphine consumption, and additional analgesic use were found to be statistically significantly higher in the 20 ml group than in the 30 ml group (p < 0.001, p = 0.001, respectively). There was no statistically significant difference between the groups in terms of side effects (p > 0.05). Conclusions The results of ESPB applied with 20 ml and 30 ml of local anesthetic before the surgical incision in thoracotomy patients showed that the use of 30 ml of local anesthetic provided more effective analgesia. In addition, similar side-effect rates show that 30 ml of local anesthetic can be used safely.https://doi.org/10.1186/s12871-023-02004-4Acute painErector spinae plane blockLocal anesthetic volumePostoperative painThoracotomy
spellingShingle Musa Zengin
Hilal Sazak
Ramazan Baldemir
Gulay Ulger
Dilara Arican
Oya Kaybal
Ali Alagoz
Comparison of analgesic efficacy of different local anesthetic volumes for erector spinae plane block in thoracotomy patients; a prospective randomized trial
BMC Anesthesiology
Acute pain
Erector spinae plane block
Local anesthetic volume
Postoperative pain
Thoracotomy
title Comparison of analgesic efficacy of different local anesthetic volumes for erector spinae plane block in thoracotomy patients; a prospective randomized trial
title_full Comparison of analgesic efficacy of different local anesthetic volumes for erector spinae plane block in thoracotomy patients; a prospective randomized trial
title_fullStr Comparison of analgesic efficacy of different local anesthetic volumes for erector spinae plane block in thoracotomy patients; a prospective randomized trial
title_full_unstemmed Comparison of analgesic efficacy of different local anesthetic volumes for erector spinae plane block in thoracotomy patients; a prospective randomized trial
title_short Comparison of analgesic efficacy of different local anesthetic volumes for erector spinae plane block in thoracotomy patients; a prospective randomized trial
title_sort comparison of analgesic efficacy of different local anesthetic volumes for erector spinae plane block in thoracotomy patients a prospective randomized trial
topic Acute pain
Erector spinae plane block
Local anesthetic volume
Postoperative pain
Thoracotomy
url https://doi.org/10.1186/s12871-023-02004-4
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