mTOR as a Potential Target for the Treatment of Microbial Infections, Inflammatory Bowel Diseases, and Colorectal Cancer
The mammalian target of rapamycin (mTOR) is the major controller of a number of important cellular activities, including protein synthesis, cell expansion, multiplication, autophagy, lysosomal function, and cellular metabolism. When mTOR interacts with specific adaptor proteins, it forms two complex...
Main Authors: | Obaid Afzal, Abdulmalik S. A. Altamimi, Bismillah Mubeen, Sami I. Alzarea, Waleed Hassan Almalki, Salwa D. Al-Qahtani, Eman M. Atiya, Fahad A. Al-Abbasi, Fatima Ali, Inam Ullah, Muhammad Shahid Nadeem, Imran Kazmi |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-10-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/23/20/12470 |
Similar Items
-
HRK inhibits colorectal cancer cells proliferation by suppressing the PI3K/AKT/mTOR pathway
by: Haowei Wang, et al.
Published: (2022-12-01) -
The mTOR Signalling Pathway in Human Cancer
by: Paula Soares, et al.
Published: (2012-02-01) -
Silibinin Downregulates Types I and III Collagen Expression via Suppression of the mTOR Signaling Pathway
by: Sooyeon Choi, et al.
Published: (2023-09-01) -
Modulating mTOR Signaling as a Promising Therapeutic Strategy for Atherosclerosis
by: Anastasia V. Poznyak, et al.
Published: (2022-01-01) -
Advances in the mTOR signaling pathway and its inhibitor rapamycin in epilepsy
by: Wei Zhao, et al.
Published: (2023-06-01)