Conserved methylation signatures associate with the tumor immune microenvironment and immunotherapy response

Conserved methylation signatures associate with the tumor immune microenvironment and immunotherapy response

Abstract Background Aberrant DNA methylation is a major characteristic of cancer genomes. It remains unclear which biological processes determine epigenetic reprogramming and how these processes influence the variants in the cancer methylome, which can further impact cancer phenotypes. Methods We pe...

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Bibliographic Details
Main Authors: Qingqing Qin, Ying Zhou, Jintao Guo, Qinwei Chen, Weiwei Tang, Yuchen Li, Jun You, Qiyuan Li
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Genome Medicine
Subjects:
DNA methylation signature
Determinant genes
DNA-binding motifs
Immunotherapy response
Online Access:https://doi.org/10.1186/s13073-024-01318-3

Internet

https://doi.org/10.1186/s13073-024-01318-3

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