The Influence of SARS-CoV-2 Pandemic on the Diagnosis of Celiac Disease and Clinical Practice in Pediatric Gastroenterology
Celiac disease (CD) has a high prevalence but remains largely underdiagnosed. Although extensive studies have confirmed that children with CD do not have an increased risk of severe COVID-19, public health regulations associated with the SARS-CoV-2 pandemic may have exacerbated this problem. The aim...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/15/3/559 |
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| author | Marco Crocco Angela Calvi Francesca Canzoneri Federica Malerba Noemi Zampatti Andrea Chiaro Serena Arrigo Paolo Gandullia Stefania Proietti Stefano Bonassi |
| author_facet | Marco Crocco Angela Calvi Francesca Canzoneri Federica Malerba Noemi Zampatti Andrea Chiaro Serena Arrigo Paolo Gandullia Stefania Proietti Stefano Bonassi |
| author_sort | Marco Crocco |
| collection | DOAJ |
| description | Celiac disease (CD) has a high prevalence but remains largely underdiagnosed. Although extensive studies have confirmed that children with CD do not have an increased risk of severe COVID-19, public health regulations associated with the SARS-CoV-2 pandemic may have exacerbated this problem. The aim of this study was to assess the effect of SARS-CoV-2 on the number of new-onset CD cases. Additionally, the role of SARS-CoV-2 in autoimmune diseases and its influence on clinical practice in pediatric gastroenterology were briefly reviewed. We described the data from the hospital electronic registry of new-onset CD, during the COVID-19 pandemic and 2 years before. A total of 423 children were diagnosed with CD between March 2018 and February 2022: 228 in the 2-year pre-COVID-19 period and 195 during the pandemic. The number of patients during the COVID-19 pandemic was 14.5% lower than in the previous years. The quarterly comparison of CD diagnoses showed a reduction in all quarters. A reduction in diagnoses during the lockdown and in the following months was evident and not compensated thereafter. This is the first study to evaluate the impact of SARS-CoV-2 on the diagnosis of CD in children. Further studies are necessary to improve the system of biopsy-sparing diagnosis and to evaluate the effect of the diagnostic delay. Special attention should be given to the implementation of telemedicine services. |
| first_indexed | 2024-03-11T09:31:40Z |
| format | Article |
| id | doaj.art-b18abd5cfd4e4432a67d9def3d27d0e3 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-11T09:31:40Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-b18abd5cfd4e4432a67d9def3d27d0e32023-11-16T17:38:38ZengMDPI AGNutrients2072-66432023-01-0115355910.3390/nu15030559The Influence of SARS-CoV-2 Pandemic on the Diagnosis of Celiac Disease and Clinical Practice in Pediatric GastroenterologyMarco Crocco0Angela Calvi1Francesca Canzoneri2Federica Malerba3Noemi Zampatti4Andrea Chiaro5Serena Arrigo6Paolo Gandullia7Stefania Proietti8Stefano Bonassi9Pediatric Gastroenterology and Endoscopy Unit, IRCCS Istituto Giannina Gaslini, 16147 Genoa, ItalyPediatric Gastroenterology and Endoscopy Unit, IRCCS Istituto Giannina Gaslini, 16147 Genoa, ItalyDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Child and Maternal Health, University of Genova, 16132 Genova, ItalyPediatric Gastroenterology and Endoscopy Unit, IRCCS Istituto Giannina Gaslini, 16147 Genoa, ItalyDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Child and Maternal Health, University of Genova, 16132 Genova, ItalyPediatric Gastroenterology and Endoscopy Unit, IRCCS Istituto Giannina Gaslini, 16147 Genoa, ItalyPediatric Gastroenterology and Endoscopy Unit, IRCCS Istituto Giannina Gaslini, 16147 Genoa, ItalyPediatric Gastroenterology and Endoscopy Unit, IRCCS Istituto Giannina Gaslini, 16147 Genoa, ItalyDepartment of Human Sciences and Quality of Life Promotion, San Raffaele University, 00166 Rome, ItalyDepartment of Human Sciences and Quality of Life Promotion, San Raffaele University, 00166 Rome, ItalyCeliac disease (CD) has a high prevalence but remains largely underdiagnosed. Although extensive studies have confirmed that children with CD do not have an increased risk of severe COVID-19, public health regulations associated with the SARS-CoV-2 pandemic may have exacerbated this problem. The aim of this study was to assess the effect of SARS-CoV-2 on the number of new-onset CD cases. Additionally, the role of SARS-CoV-2 in autoimmune diseases and its influence on clinical practice in pediatric gastroenterology were briefly reviewed. We described the data from the hospital electronic registry of new-onset CD, during the COVID-19 pandemic and 2 years before. A total of 423 children were diagnosed with CD between March 2018 and February 2022: 228 in the 2-year pre-COVID-19 period and 195 during the pandemic. The number of patients during the COVID-19 pandemic was 14.5% lower than in the previous years. The quarterly comparison of CD diagnoses showed a reduction in all quarters. A reduction in diagnoses during the lockdown and in the following months was evident and not compensated thereafter. This is the first study to evaluate the impact of SARS-CoV-2 on the diagnosis of CD in children. Further studies are necessary to improve the system of biopsy-sparing diagnosis and to evaluate the effect of the diagnostic delay. Special attention should be given to the implementation of telemedicine services.https://www.mdpi.com/2072-6643/15/3/559celiac diseaseCOVID-19SARS-CoV-2pandemicpediatric gastroenterologylockdown |
| spellingShingle | Marco Crocco Angela Calvi Francesca Canzoneri Federica Malerba Noemi Zampatti Andrea Chiaro Serena Arrigo Paolo Gandullia Stefania Proietti Stefano Bonassi The Influence of SARS-CoV-2 Pandemic on the Diagnosis of Celiac Disease and Clinical Practice in Pediatric Gastroenterology Nutrients celiac disease COVID-19 SARS-CoV-2 pandemic pediatric gastroenterology lockdown |
| title | The Influence of SARS-CoV-2 Pandemic on the Diagnosis of Celiac Disease and Clinical Practice in Pediatric Gastroenterology |
| title_full | The Influence of SARS-CoV-2 Pandemic on the Diagnosis of Celiac Disease and Clinical Practice in Pediatric Gastroenterology |
| title_fullStr | The Influence of SARS-CoV-2 Pandemic on the Diagnosis of Celiac Disease and Clinical Practice in Pediatric Gastroenterology |
| title_full_unstemmed | The Influence of SARS-CoV-2 Pandemic on the Diagnosis of Celiac Disease and Clinical Practice in Pediatric Gastroenterology |
| title_short | The Influence of SARS-CoV-2 Pandemic on the Diagnosis of Celiac Disease and Clinical Practice in Pediatric Gastroenterology |
| title_sort | influence of sars cov 2 pandemic on the diagnosis of celiac disease and clinical practice in pediatric gastroenterology |
| topic | celiac disease COVID-19 SARS-CoV-2 pandemic pediatric gastroenterology lockdown |
| url | https://www.mdpi.com/2072-6643/15/3/559 |
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