Bibliometric and visual analysis of nephrotoxicity research worldwide
Background: Nephrotoxicity of drugs contributes to acute kidney injury with high mortality and morbidity, which crucially limits the application and development of drugs. Although many publications on nephrotoxicity have been conducted globally, there needs to be a scientometric study to systematica...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2022.940791/full |
| _version_ | 1798036063365627904 |
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| author | Tianmu He Tianmu He Jingwen Ao Cancan Duan Rong Yan Xiaomei Li Liu Liu Jianyong Zhang Xiaofei Li Xiaofei Li |
| author_facet | Tianmu He Tianmu He Jingwen Ao Cancan Duan Rong Yan Xiaomei Li Liu Liu Jianyong Zhang Xiaofei Li Xiaofei Li |
| author_sort | Tianmu He |
| collection | DOAJ |
| description | Background: Nephrotoxicity of drugs contributes to acute kidney injury with high mortality and morbidity, which crucially limits the application and development of drugs. Although many publications on nephrotoxicity have been conducted globally, there needs to be a scientometric study to systematically analyze the intellectual landscape and frontiers research trends in the future.Methods: Publications on nephrotoxicity from 2011 to 2021 were collected to perform bibliometric visualization using VOSviewer, CiteSpace, and Scimago Graphica software based on the Web of Science Core Collection.Results: A total of 9,342 documents were analyzed, which were primarily published in the United States (1,861), China (1,724), and Egypt (701). For institutions, King Saud University (166) had the most publications; Food and Chemical Toxicology, PLOS One, and Antimicrobial Agents and Chemotherapy were productive journals, primarily concentrating on the mechanisms of nephrotoxicity and renoprotective in cisplatin and antibiotics, especially in oxidative stress. Burst detection suggested that cisplatin, piperacillin-tazobactam, vancomycin-induced nephrotoxicity, antioxidants, and new biomaterials are frontiers of research.Conclusion: This study first provides an updated perspective on nephrotoxicity and renoprotective strategies and mechanisms. This perspective may benefit researchers in choosing suitable journals and collaborators and assisting them in the deep understanding of the nephrotoxicity and renoprotective hotspots and frontiers. |
| first_indexed | 2024-04-11T21:07:08Z |
| format | Article |
| id | doaj.art-b18c59a2cc5544cea0a0be521d00edd2 |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-04-11T21:07:08Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-b18c59a2cc5544cea0a0be521d00edd22022-12-22T04:03:15ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122022-09-011310.3389/fphar.2022.940791940791Bibliometric and visual analysis of nephrotoxicity research worldwideTianmu He0Tianmu He1Jingwen Ao2Cancan Duan3Rong Yan4Xiaomei Li5Liu Liu6Jianyong Zhang7Xiaofei Li8Xiaofei Li9School of Basic Medical Sciences, Guizhou Medical University, Guiyang, ChinaSchool of Basic Medical Sciences, Zunyi Medical University, Zunyi, ChinaSchool of Pharmacy and Key Laboratory of Basic Pharmacology Ministry Education and Joint International Research Laboratory of Ethnomedicine Ministry of Education, Zunyi Medical University, Zunyi, ChinaSchool of Pharmacy and Key Laboratory of Basic Pharmacology Ministry Education and Joint International Research Laboratory of Ethnomedicine Ministry of Education, Zunyi Medical University, Zunyi, ChinaSchool of Basic Medical Sciences, Zunyi Medical University, Zunyi, ChinaAffiliated Hospital of Zunyi Medical University, Zunyi, ChinaSchool of Basic Medical Sciences, Zunyi Medical University, Zunyi, ChinaSchool of Pharmacy and Key Laboratory of Basic Pharmacology Ministry Education and Joint International Research Laboratory of Ethnomedicine Ministry of Education, Zunyi Medical University, Zunyi, ChinaSchool of Basic Medical Sciences, Guizhou Medical University, Guiyang, ChinaSchool of Basic Medical Sciences, Zunyi Medical University, Zunyi, ChinaBackground: Nephrotoxicity of drugs contributes to acute kidney injury with high mortality and morbidity, which crucially limits the application and development of drugs. Although many publications on nephrotoxicity have been conducted globally, there needs to be a scientometric study to systematically analyze the intellectual landscape and frontiers research trends in the future.Methods: Publications on nephrotoxicity from 2011 to 2021 were collected to perform bibliometric visualization using VOSviewer, CiteSpace, and Scimago Graphica software based on the Web of Science Core Collection.Results: A total of 9,342 documents were analyzed, which were primarily published in the United States (1,861), China (1,724), and Egypt (701). For institutions, King Saud University (166) had the most publications; Food and Chemical Toxicology, PLOS One, and Antimicrobial Agents and Chemotherapy were productive journals, primarily concentrating on the mechanisms of nephrotoxicity and renoprotective in cisplatin and antibiotics, especially in oxidative stress. Burst detection suggested that cisplatin, piperacillin-tazobactam, vancomycin-induced nephrotoxicity, antioxidants, and new biomaterials are frontiers of research.Conclusion: This study first provides an updated perspective on nephrotoxicity and renoprotective strategies and mechanisms. This perspective may benefit researchers in choosing suitable journals and collaborators and assisting them in the deep understanding of the nephrotoxicity and renoprotective hotspots and frontiers.https://www.frontiersin.org/articles/10.3389/fphar.2022.940791/fullacute kidney injurybibliometricsnephrotoxicity mechanismrenoprotective strategieshotspot |
| spellingShingle | Tianmu He Tianmu He Jingwen Ao Cancan Duan Rong Yan Xiaomei Li Liu Liu Jianyong Zhang Xiaofei Li Xiaofei Li Bibliometric and visual analysis of nephrotoxicity research worldwide Frontiers in Pharmacology acute kidney injury bibliometrics nephrotoxicity mechanism renoprotective strategies hotspot |
| title | Bibliometric and visual analysis of nephrotoxicity research worldwide |
| title_full | Bibliometric and visual analysis of nephrotoxicity research worldwide |
| title_fullStr | Bibliometric and visual analysis of nephrotoxicity research worldwide |
| title_full_unstemmed | Bibliometric and visual analysis of nephrotoxicity research worldwide |
| title_short | Bibliometric and visual analysis of nephrotoxicity research worldwide |
| title_sort | bibliometric and visual analysis of nephrotoxicity research worldwide |
| topic | acute kidney injury bibliometrics nephrotoxicity mechanism renoprotective strategies hotspot |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2022.940791/full |
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