Who has anaphylaxis in Brazil? Validation of a questionnaire for population studies
Background The incidence of anaphylaxis is increasing in several parts of the world; thus, determining the prevalence of the disease in a given region is important to understand the factors involved and to promote measures to avoid this type of allergic reaction. Aiming this objective, we validated...
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| Format: | Article |
| Language: | English |
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Elsevier
2017-01-01
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| Series: | World Allergy Organization Journal |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1939455119300389 |
| _version_ | 1818305423408627712 |
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| author | Elaine Gagete Lucilene Delazari dos Santos Leticia Gomes de Pontes Fábio Morato Castro |
| author_facet | Elaine Gagete Lucilene Delazari dos Santos Leticia Gomes de Pontes Fábio Morato Castro |
| author_sort | Elaine Gagete |
| collection | DOAJ |
| description | Background The incidence of anaphylaxis is increasing in several parts of the world; thus, determining the prevalence of the disease in a given region is important to understand the factors involved and to promote measures to avoid this type of allergic reaction. Aiming this objective, we validated an instrument for a population-basedstudy that assesses the prevalence of anaphylaxis in the Brazilian population.Methods A questionnaire was generated in two variants - one for subjects seven years old or above (Group A) and another for children who were up to six years, 11 months and 29 days (Group B). The instrument was administered to patients with and without anaphylaxis. By allocating points, a score was calculated to differentiate subjects with and without the disease. After validation, the questionnaire was applied in the city of Botucatu (São Paulo state, Brazil), by randomly selecting houses and inviting residents to answer the questionnaire.Results The questionnaire was reliable for identifying subjects with and without anaphylaxis in both groups, with a specificity and sensitivity above 90%. The prevalence of anaphylaxis in the pilot survey was 6.2% in Group A, however the evaluation was compromised in Group B by the low number of children below seven years of age due to random sampling of residences.Discussion The prevalence of anaphylaxis in our pilot test (6.2%) was similar to major epidemiological surveys from several parts of the world, showing that anaphylaxis is not a rare disease. The instrument of the present work was suitable for this epidemiological survey and might be a good option for studying anaphylaxis in other populations.Conclusion This instrument might be of particular value in places where researchers cannot access medical records to conduct similar epidemiological studies. Keywords: Anaphylaxis, Epidemiology, Surveys and questionnaires |
| first_indexed | 2024-12-13T06:26:21Z |
| format | Article |
| id | doaj.art-b18d8ef8abbf49dc96413967c964ca7a |
| institution | Directory Open Access Journal |
| issn | 1939-4551 |
| language | English |
| last_indexed | 2024-12-13T06:26:21Z |
| publishDate | 2017-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | World Allergy Organization Journal |
| spelling | doaj.art-b18d8ef8abbf49dc96413967c964ca7a2022-12-21T23:56:44ZengElsevierWorld Allergy Organization Journal1939-45512017-01-01101Who has anaphylaxis in Brazil? Validation of a questionnaire for population studiesElaine Gagete0Lucilene Delazari dos Santos1Leticia Gomes de Pontes2Fábio Morato Castro3Faculdade de MedicinaUniversidade de São Paulo (Medical School of University of Sao Paulo (USP), Rua Tenente Silvio Bestetti 590, Botucatu, SP, Brazil; Correspondence:CEVAP, Universidade Estadual Paulista – Botucatu (São Paulo State University - UNESP- Botucatu), Sao Paulo, BrazilCEVAP, Universidade Estadual Paulista – Botucatu (São Paulo State University - UNESP- Botucatu), Sao Paulo, BrazilFaculdade de MedicinaUniversidade de São Paulo (Medical School of University of Sao Paulo (USP), Rua Tenente Silvio Bestetti 590, Botucatu, SP, BrazilBackground The incidence of anaphylaxis is increasing in several parts of the world; thus, determining the prevalence of the disease in a given region is important to understand the factors involved and to promote measures to avoid this type of allergic reaction. Aiming this objective, we validated an instrument for a population-basedstudy that assesses the prevalence of anaphylaxis in the Brazilian population.Methods A questionnaire was generated in two variants - one for subjects seven years old or above (Group A) and another for children who were up to six years, 11 months and 29 days (Group B). The instrument was administered to patients with and without anaphylaxis. By allocating points, a score was calculated to differentiate subjects with and without the disease. After validation, the questionnaire was applied in the city of Botucatu (São Paulo state, Brazil), by randomly selecting houses and inviting residents to answer the questionnaire.Results The questionnaire was reliable for identifying subjects with and without anaphylaxis in both groups, with a specificity and sensitivity above 90%. The prevalence of anaphylaxis in the pilot survey was 6.2% in Group A, however the evaluation was compromised in Group B by the low number of children below seven years of age due to random sampling of residences.Discussion The prevalence of anaphylaxis in our pilot test (6.2%) was similar to major epidemiological surveys from several parts of the world, showing that anaphylaxis is not a rare disease. The instrument of the present work was suitable for this epidemiological survey and might be a good option for studying anaphylaxis in other populations.Conclusion This instrument might be of particular value in places where researchers cannot access medical records to conduct similar epidemiological studies. Keywords: Anaphylaxis, Epidemiology, Surveys and questionnaireshttp://www.sciencedirect.com/science/article/pii/S1939455119300389 |
| spellingShingle | Elaine Gagete Lucilene Delazari dos Santos Leticia Gomes de Pontes Fábio Morato Castro Who has anaphylaxis in Brazil? Validation of a questionnaire for population studies World Allergy Organization Journal |
| title | Who has anaphylaxis in Brazil? Validation of a questionnaire for population studies |
| title_full | Who has anaphylaxis in Brazil? Validation of a questionnaire for population studies |
| title_fullStr | Who has anaphylaxis in Brazil? Validation of a questionnaire for population studies |
| title_full_unstemmed | Who has anaphylaxis in Brazil? Validation of a questionnaire for population studies |
| title_short | Who has anaphylaxis in Brazil? Validation of a questionnaire for population studies |
| title_sort | who has anaphylaxis in brazil validation of a questionnaire for population studies |
| url | http://www.sciencedirect.com/science/article/pii/S1939455119300389 |
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