Topical Treatment Modalities for Old World Cutaneous Leishmaniasis: A Review
Diagnosis and therapy of cutaneous leishmaniasis (CL) can be difficult due to the variability of the clinical pictures and resistance to therapy. There is no vaccine currently available for CL. The aim of the present review is to describe different topical treatment modalities for old world CL. The...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Karolinum Press
2012-01-01
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| Series: | Prague Medical Report |
| Subjects: | |
| Online Access: | https://pmr.lf1.cuni.cz/113/2/0105/ |
| _version_ | 1818176395806769152 |
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| author | R. Alavi-Naini Asghar Fazaeli T. O'Dempsey |
| author_facet | R. Alavi-Naini Asghar Fazaeli T. O'Dempsey |
| author_sort | R. Alavi-Naini |
| collection | DOAJ |
| description | Diagnosis and therapy of cutaneous leishmaniasis (CL) can be difficult due to the variability of the clinical pictures and resistance to therapy. There is no vaccine currently available for CL. The aim of the present review is to describe different topical treatment modalities for old world CL. The mainstays of treatment for old world CL are pentavalent antimony compounds which are administered parenterally or intralesionally. New topical treatment alternatives have been available within the past few years. Amongst several treatments used topically, physical therapies including cryotherapy, heat therapy and CO2 laser are promising for the treatment of old world CL. Along with that, other randomized placebo controlled trials should be designed to find new effective therapeutic regimens. |
| first_indexed | 2024-12-11T20:15:31Z |
| format | Article |
| id | doaj.art-b19086cf974844a698fe30d456f66ac0 |
| institution | Directory Open Access Journal |
| issn | 1214-6994 2336-2936 |
| language | English |
| last_indexed | 2024-12-11T20:15:31Z |
| publishDate | 2012-01-01 |
| publisher | Karolinum Press |
| record_format | Article |
| series | Prague Medical Report |
| spelling | doaj.art-b19086cf974844a698fe30d456f66ac02022-12-22T00:52:12ZengKarolinum PressPrague Medical Report1214-69942336-29362012-01-01113210511810.14712/23362936.2015.26Topical Treatment Modalities for Old World Cutaneous Leishmaniasis: A ReviewR. Alavi-Naini0Asghar Fazaeli1T. O'Dempsey2Research Centre for Infectious Diseases and Tropical Medicine, Zahedan University of Medical Sciences, Zahedan, IranDepartment of Parasitology, School of Medicine, Zanjan University of Medical Sciences and Health Services, Zanjan, IranLiverpool School of Tropical Medicine, Liverpool, UKDiagnosis and therapy of cutaneous leishmaniasis (CL) can be difficult due to the variability of the clinical pictures and resistance to therapy. There is no vaccine currently available for CL. The aim of the present review is to describe different topical treatment modalities for old world CL. The mainstays of treatment for old world CL are pentavalent antimony compounds which are administered parenterally or intralesionally. New topical treatment alternatives have been available within the past few years. Amongst several treatments used topically, physical therapies including cryotherapy, heat therapy and CO2 laser are promising for the treatment of old world CL. Along with that, other randomized placebo controlled trials should be designed to find new effective therapeutic regimens.https://pmr.lf1.cuni.cz/113/2/0105/Cutaneous leishmaniasisOld worldTopical treatment |
| spellingShingle | R. Alavi-Naini Asghar Fazaeli T. O'Dempsey Topical Treatment Modalities for Old World Cutaneous Leishmaniasis: A Review Prague Medical Report Cutaneous leishmaniasis Old world Topical treatment |
| title | Topical Treatment Modalities for Old World Cutaneous Leishmaniasis: A Review |
| title_full | Topical Treatment Modalities for Old World Cutaneous Leishmaniasis: A Review |
| title_fullStr | Topical Treatment Modalities for Old World Cutaneous Leishmaniasis: A Review |
| title_full_unstemmed | Topical Treatment Modalities for Old World Cutaneous Leishmaniasis: A Review |
| title_short | Topical Treatment Modalities for Old World Cutaneous Leishmaniasis: A Review |
| title_sort | topical treatment modalities for old world cutaneous leishmaniasis a review |
| topic | Cutaneous leishmaniasis Old world Topical treatment |
| url | https://pmr.lf1.cuni.cz/113/2/0105/ |
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