Interaction between cytochrome P450 2A6 and Catechol-O-Methyltransferase genes and their association with smoking risk in young men

Interaction between cytochrome P450 2A6 and Catechol-O-Methyltransferase genes and their association with smoking risk in young men

Abstract Background Although some effects of gene–gene interactions on nicotine–dopamine metabolism for smoking behavior have been reported, polymorphisms of cytochrome P450 (CYP) 2A6 and catechol-O-methyltransferase (COMT) have not been studied together to determine their effects on smokers. The ai...

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Bibliographic Details
Main Authors: Wei-Chih Ou, Yi-Chin Huang, Chih-Ling Huang, Min-Hsuan Lin, Yi-Chun Chen, Yi-Ju Chen, Chen-Nu Liu, Mei-Chih Chen, Ching-Shan Huang, Pei-Lain Chen
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Behavioral and Brain Functions
Subjects:
Catechol-O-methyltransferase
Cotinine
Cytochrome P450 2A6
Nicotine
Smoking status
Online Access:http://link.springer.com/article/10.1186/s12993-017-0127-2

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