Evidence of a Muscle–Brain Axis by Quantification of the Neurotrophic Myokine METRNL (Meteorin-Like Protein) in Human Cerebrospinal Fluid and Serum

Evidence of a Muscle–Brain Axis by Quantification of the Neurotrophic Myokine METRNL (Meteorin-Like Protein) in Human Cerebrospinal Fluid and Serum

Data on the quantification of the potentially neurotrophic adipo-myokine METRNL (Meteorin-like protein) in human cerebrospinal fluid (CSF) are lacking and migration of this secreted protein across the blood–brain barrier (BBB) is uncertain. In the present pilot study, METRNL concentrations were quan...

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Bibliographic Details
Main Authors: Martin Berghoff, Alexandra Höpfinger, Ranjithkumar Rajendran, Thomas Karrasch, Andreas Schmid, Andreas Schäffler
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Journal of Clinical Medicine
Subjects:
myokine
METRNL (Meteorin-like protein)
cerebrospinal fluid
blood–brain barrier
adipokine
Online Access:https://www.mdpi.com/2077-0383/10/15/3271

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