iPLA2β overexpression in smooth muscle exacerbates angiotensin II-induced hypertension and vascular remodeling.

iPLA2β overexpression in smooth muscle exacerbates angiotensin II-induced hypertension and vascular remodeling.

Calcium independent group VIA phospholipase A(2) (iPLA(2)β) is up-regulated in vascular smooth muscle cells in some diseases, but whether the up-regulated iPLA(2)β affects vascular morphology and blood pressure is unknown. The current study addresses this question by evaluating the basal- and angiot...

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Bibliographic Details
Main Authors: Lindsay E Calderon, Shu Liu, Wen Su, Zhongwen Xie, Zhenheng Guo, Wanda Eberhard, Ming C Gong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3282780?pdf=render

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