Management of obsessive compulsive disorder induced by the use of clozapine

The second generation antipsychotic of clozapine has superior efficacy compared to other antipsychotics especially for treatment-resistant schizophrenia. In up to 20% of patients receiving clozapine treatment, the side effect of obsessive compulsive symptoms or obsessive compulsive disorder occurs....

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Main Authors: Yunus Emre Donmez, Ozlem Ozcan, Fatma Kartal Sarioglu, Sumeyra Gungoren
Format: Article
Language:English
Published: Society of Turaz Bilim 2019-06-01
Series:Medicine Science
Subjects:
Online Access:http://www.ejmanager.com/fulltextpdf.php?mno=302643025
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author Yunus Emre Donmez
Ozlem Ozcan
Fatma Kartal Sarioglu
Sumeyra Gungoren
author_facet Yunus Emre Donmez
Ozlem Ozcan
Fatma Kartal Sarioglu
Sumeyra Gungoren
author_sort Yunus Emre Donmez
collection DOAJ
description The second generation antipsychotic of clozapine has superior efficacy compared to other antipsychotics especially for treatment-resistant schizophrenia. In up to 20% of patients receiving clozapine treatment, the side effect of obsessive compulsive symptoms or obsessive compulsive disorder occurs. These obsessive compulsive side effects sometimes cause cessation of the use of clozapine and sometimes causes difficulties in treating the psychotic symptoms due to dose reductions. This manuscript presents a case with resistant schizophrenia who developed obsessive compulsive disorder secondary to clozapine treatment and was successfully treated with clomipramine and aims to discuss the case accompanied by the literature. [Med-Science 2019; 8(2.000): 449-50]
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spelling doaj.art-b1993ccf4ea74afd99edfd49e7e4479b2024-02-03T08:38:20ZengSociety of Turaz BilimMedicine Science2147-06342019-06-01824495010.5455/medscience.2018.07.8920302643025Management of obsessive compulsive disorder induced by the use of clozapineYunus Emre Donmez0Ozlem Ozcan1Fatma Kartal Sarioglu2Sumeyra Gungoren3Department of Child and Adolescent Psychiatry, Malatya Training and Research Hospital, Malatya,Turkey Department of Child and Adolescent Psychiatry, Inonu University, Faculty of Medicine, Malatya, Turkey Department of Psychiatry, Inonu University, Malatya/Turkey Department of Child and Adolescent Psychiatry, Harran University, Sanliurfa, TurkeyThe second generation antipsychotic of clozapine has superior efficacy compared to other antipsychotics especially for treatment-resistant schizophrenia. In up to 20% of patients receiving clozapine treatment, the side effect of obsessive compulsive symptoms or obsessive compulsive disorder occurs. These obsessive compulsive side effects sometimes cause cessation of the use of clozapine and sometimes causes difficulties in treating the psychotic symptoms due to dose reductions. This manuscript presents a case with resistant schizophrenia who developed obsessive compulsive disorder secondary to clozapine treatment and was successfully treated with clomipramine and aims to discuss the case accompanied by the literature. [Med-Science 2019; 8(2.000): 449-50]http://www.ejmanager.com/fulltextpdf.php?mno=302643025atypical antipsychoticsclozapineobsessive compulsive disorderclomipramineadolescent
spellingShingle Yunus Emre Donmez
Ozlem Ozcan
Fatma Kartal Sarioglu
Sumeyra Gungoren
Management of obsessive compulsive disorder induced by the use of clozapine
Medicine Science
atypical antipsychotics
clozapine
obsessive compulsive disorder
clomipramine
adolescent
title Management of obsessive compulsive disorder induced by the use of clozapine
title_full Management of obsessive compulsive disorder induced by the use of clozapine
title_fullStr Management of obsessive compulsive disorder induced by the use of clozapine
title_full_unstemmed Management of obsessive compulsive disorder induced by the use of clozapine
title_short Management of obsessive compulsive disorder induced by the use of clozapine
title_sort management of obsessive compulsive disorder induced by the use of clozapine
topic atypical antipsychotics
clozapine
obsessive compulsive disorder
clomipramine
adolescent
url http://www.ejmanager.com/fulltextpdf.php?mno=302643025
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