Novel Ratio Soluble Fms-like Tyrosine Kinase-1/Angiotensin-II (sFlt-1/ANG-II) in Pregnant Women Is Associated with Critical Illness in COVID-19

Novel Ratio Soluble Fms-like Tyrosine Kinase-1/Angiotensin-II (sFlt-1/ANG-II) in Pregnant Women Is Associated with Critical Illness in COVID-19

Background: In healthy pregnancies, components of the Renin-Angiotensin system (RAS) are present in the placental villi and contribute to invasion, migration, and angiogenesis. At the same time, soluble fms-like tyrosine kinase 1 (sFlt-1) production is induced after binding of ANG-II to its receptor...

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Bibliographic Details
Main Authors: Salvador Espino-y-Sosa, Raigam Jafet Martinez-Portilla, Johnatan Torres-Torres, Juan Mario Solis-Paredes, Guadalupe Estrada-Gutierrez, Jose Antonio Hernandez-Pacheco, Aurora Espejel-Nuñez, Paloma Mateu-Rogell, Angeles Juarez-Reyes, Francisco Eduardo Lopez-Ceh, Jose Rafael Villafan-Bernal, Lourdes Rojas-Zepeda, Iris Paola Guzman-Guzman, Liona C. Poon
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Viruses
Subjects:
COVID-19
maternal death
angiotensin-II
sFlt-1
Online Access:https://www.mdpi.com/1999-4915/13/10/1906

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