Surface Modification of Biomedical Ti and Ti Alloys: A Review on Current Advances

Ti is widely used as a material for orthopedic implants. As rapid and effective osseointegration is a key factor for the successful application of implants, biologically inert Ti materials start to show inherent limitations, such as poor surface cell adhesion, bioactivity, and bone-growth-inducing c...

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Main Authors: Jingyuan Xu, Jiawen Zhang, Yangfan Shi, Jincheng Tang, Danni Huang, Ming Yan, Matthew S. Dargusch
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Materials
Subjects:
Online Access:https://www.mdpi.com/1996-1944/15/5/1749
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author Jingyuan Xu
Jiawen Zhang
Yangfan Shi
Jincheng Tang
Danni Huang
Ming Yan
Matthew S. Dargusch
author_facet Jingyuan Xu
Jiawen Zhang
Yangfan Shi
Jincheng Tang
Danni Huang
Ming Yan
Matthew S. Dargusch
author_sort Jingyuan Xu
collection DOAJ
description Ti is widely used as a material for orthopedic implants. As rapid and effective osseointegration is a key factor for the successful application of implants, biologically inert Ti materials start to show inherent limitations, such as poor surface cell adhesion, bioactivity, and bone-growth-inducing capabilities. Surface modification can be an efficient and effective approach to addressing the biocompatibility, mechanical, and functionality issues of the various Ti implant materials. In this study, we have overviewed more than 140 papers to summarize the recent progress in the surface modification of Ti implants by physical and/or chemical modification approaches, aiming at optimizing their wear resistance, biocompatibility, and antimicrobial properties. As an advanced manufacturing technology for Ti and Ti alloys, additive manufacturing was particularly addressed in this review. We also provide an outlook for future research directions in this field as a contribution to the development of advanced Ti implants for biomedical applications.
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spelling doaj.art-b19f486f46414e30814e80b69c51bc542023-11-23T23:18:17ZengMDPI AGMaterials1996-19442022-02-01155174910.3390/ma15051749Surface Modification of Biomedical Ti and Ti Alloys: A Review on Current AdvancesJingyuan Xu0Jiawen Zhang1Yangfan Shi2Jincheng Tang3Danni Huang4Ming Yan5Matthew S. Dargusch6School of Mechanical and Mining Engineering, The University of Queensland, Brisbane 4072, AustraliaDepartment of Materials Science and Engineering, Southern University of Science and Technology, Shenzhen 518055, ChinaDepartment of Materials Science and Engineering, Southern University of Science and Technology, Shenzhen 518055, ChinaDepartment of Materials Science and Engineering, Southern University of Science and Technology, Shenzhen 518055, ChinaDepartment of Materials Science and Engineering, Southern University of Science and Technology, Shenzhen 518055, ChinaDepartment of Materials Science and Engineering, Southern University of Science and Technology, Shenzhen 518055, ChinaDepartment of Materials Science and Engineering, Southern University of Science and Technology, Shenzhen 518055, ChinaTi is widely used as a material for orthopedic implants. As rapid and effective osseointegration is a key factor for the successful application of implants, biologically inert Ti materials start to show inherent limitations, such as poor surface cell adhesion, bioactivity, and bone-growth-inducing capabilities. Surface modification can be an efficient and effective approach to addressing the biocompatibility, mechanical, and functionality issues of the various Ti implant materials. In this study, we have overviewed more than 140 papers to summarize the recent progress in the surface modification of Ti implants by physical and/or chemical modification approaches, aiming at optimizing their wear resistance, biocompatibility, and antimicrobial properties. As an advanced manufacturing technology for Ti and Ti alloys, additive manufacturing was particularly addressed in this review. We also provide an outlook for future research directions in this field as a contribution to the development of advanced Ti implants for biomedical applications.https://www.mdpi.com/1996-1944/15/5/1749additive manufacturingTi and Ti alloysbiomaterialsurface modificationimplant
spellingShingle Jingyuan Xu
Jiawen Zhang
Yangfan Shi
Jincheng Tang
Danni Huang
Ming Yan
Matthew S. Dargusch
Surface Modification of Biomedical Ti and Ti Alloys: A Review on Current Advances
Materials
additive manufacturing
Ti and Ti alloys
biomaterial
surface modification
implant
title Surface Modification of Biomedical Ti and Ti Alloys: A Review on Current Advances
title_full Surface Modification of Biomedical Ti and Ti Alloys: A Review on Current Advances
title_fullStr Surface Modification of Biomedical Ti and Ti Alloys: A Review on Current Advances
title_full_unstemmed Surface Modification of Biomedical Ti and Ti Alloys: A Review on Current Advances
title_short Surface Modification of Biomedical Ti and Ti Alloys: A Review on Current Advances
title_sort surface modification of biomedical ti and ti alloys a review on current advances
topic additive manufacturing
Ti and Ti alloys
biomaterial
surface modification
implant
url https://www.mdpi.com/1996-1944/15/5/1749
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AT yangfanshi surfacemodificationofbiomedicaltiandtialloysareviewoncurrentadvances
AT jinchengtang surfacemodificationofbiomedicaltiandtialloysareviewoncurrentadvances
AT dannihuang surfacemodificationofbiomedicaltiandtialloysareviewoncurrentadvances
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