Synthetic double inversion recovery imaging in brain MRI: quantitative evaluation and feasibility of synthetic MRI and a comparison with conventional double inversion recovery and fluid-attenuated inversion recovery sequences
Abstract Background and purpose Synthetic MR imaging (SyMRI) allows the reconstruction of various contrast images, including double inversion recovery (DIR), from a single scan. This study aimed to investigate the advantages of SyMRI by comparing synthetic DIR images with synthetic T2-weighted fluid...
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| Format: | Article |
| Language: | English |
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BMC
2022-10-01
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| Series: | BMC Medical Imaging |
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| Online Access: | https://doi.org/10.1186/s12880-022-00877-4 |
| _version_ | 1811197972943208448 |
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| author | Odgerel Zorigt Takahito Nakajima Yuka Kumasaka Akiko Jingu Yoshito Tsushima |
| author_facet | Odgerel Zorigt Takahito Nakajima Yuka Kumasaka Akiko Jingu Yoshito Tsushima |
| author_sort | Odgerel Zorigt |
| collection | DOAJ |
| description | Abstract Background and purpose Synthetic MR imaging (SyMRI) allows the reconstruction of various contrast images, including double inversion recovery (DIR), from a single scan. This study aimed to investigate the advantages of SyMRI by comparing synthetic DIR images with synthetic T2-weighted fluid-attenuated inversion recovery (T2W-FLAIR) and conventional DIR images. Materials and methods We retrospectively reviewed the imaging data of 100 consecutive patients who underwent brain MRI between December 2018 and March 2019. Synthetic DIR, T2W-FLAIR, T1-weighted, and phase-sensitive inversion recovery (PSIR) images were generated from SyMRI data. For synthetic DIR, the two inversion times required to suppress white matter and cerebrospinal fluid (CSF) were manually determined by two radiologists. Quantitative analysis was performed by manually tracing the region of interest (ROI) at the sites of the lesion, white matter, and CSF. Synthetic DIR, synthetic T2W-FLAIR, and conventional DIR images were compared on the basis of using the gray matter-to-white matter, lesion-to-white matter, and lesion-to-CSF contrast-to-noise ratios. Results The two radiologists showed no differences in setting inversion time (TI) values, and their evaluations showed excellent interobserver agreement. The mean signal intensities obtained with synthetic DIR were significantly higher than those obtained with synthetic T2W-FLAIR and conventional DIR. Conclusion Synthetic DIR images showed a higher contrast than synthetic T2WFLAIR and conventional DIR images. |
| first_indexed | 2024-04-12T01:23:26Z |
| format | Article |
| id | doaj.art-b1a8a971755644fc95ac6e5eccd10fab |
| institution | Directory Open Access Journal |
| issn | 1471-2342 |
| language | English |
| last_indexed | 2024-04-12T01:23:26Z |
| publishDate | 2022-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Medical Imaging |
| spelling | doaj.art-b1a8a971755644fc95ac6e5eccd10fab2022-12-22T03:53:44ZengBMCBMC Medical Imaging1471-23422022-10-012211710.1186/s12880-022-00877-4Synthetic double inversion recovery imaging in brain MRI: quantitative evaluation and feasibility of synthetic MRI and a comparison with conventional double inversion recovery and fluid-attenuated inversion recovery sequencesOdgerel Zorigt0Takahito Nakajima1Yuka Kumasaka2Akiko Jingu3Yoshito Tsushima4Department of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School of MedicineDepartment of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School of MedicineDepartment of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School of MedicineDepartment of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School of MedicineDepartment of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School of MedicineAbstract Background and purpose Synthetic MR imaging (SyMRI) allows the reconstruction of various contrast images, including double inversion recovery (DIR), from a single scan. This study aimed to investigate the advantages of SyMRI by comparing synthetic DIR images with synthetic T2-weighted fluid-attenuated inversion recovery (T2W-FLAIR) and conventional DIR images. Materials and methods We retrospectively reviewed the imaging data of 100 consecutive patients who underwent brain MRI between December 2018 and March 2019. Synthetic DIR, T2W-FLAIR, T1-weighted, and phase-sensitive inversion recovery (PSIR) images were generated from SyMRI data. For synthetic DIR, the two inversion times required to suppress white matter and cerebrospinal fluid (CSF) were manually determined by two radiologists. Quantitative analysis was performed by manually tracing the region of interest (ROI) at the sites of the lesion, white matter, and CSF. Synthetic DIR, synthetic T2W-FLAIR, and conventional DIR images were compared on the basis of using the gray matter-to-white matter, lesion-to-white matter, and lesion-to-CSF contrast-to-noise ratios. Results The two radiologists showed no differences in setting inversion time (TI) values, and their evaluations showed excellent interobserver agreement. The mean signal intensities obtained with synthetic DIR were significantly higher than those obtained with synthetic T2W-FLAIR and conventional DIR. Conclusion Synthetic DIR images showed a higher contrast than synthetic T2WFLAIR and conventional DIR images.https://doi.org/10.1186/s12880-022-00877-4Magnetic resonance imagingSynthetic magnetic resonance imagingDouble inversion recoveryInversion recovery |
| spellingShingle | Odgerel Zorigt Takahito Nakajima Yuka Kumasaka Akiko Jingu Yoshito Tsushima Synthetic double inversion recovery imaging in brain MRI: quantitative evaluation and feasibility of synthetic MRI and a comparison with conventional double inversion recovery and fluid-attenuated inversion recovery sequences BMC Medical Imaging Magnetic resonance imaging Synthetic magnetic resonance imaging Double inversion recovery Inversion recovery |
| title | Synthetic double inversion recovery imaging in brain MRI: quantitative evaluation and feasibility of synthetic MRI and a comparison with conventional double inversion recovery and fluid-attenuated inversion recovery sequences |
| title_full | Synthetic double inversion recovery imaging in brain MRI: quantitative evaluation and feasibility of synthetic MRI and a comparison with conventional double inversion recovery and fluid-attenuated inversion recovery sequences |
| title_fullStr | Synthetic double inversion recovery imaging in brain MRI: quantitative evaluation and feasibility of synthetic MRI and a comparison with conventional double inversion recovery and fluid-attenuated inversion recovery sequences |
| title_full_unstemmed | Synthetic double inversion recovery imaging in brain MRI: quantitative evaluation and feasibility of synthetic MRI and a comparison with conventional double inversion recovery and fluid-attenuated inversion recovery sequences |
| title_short | Synthetic double inversion recovery imaging in brain MRI: quantitative evaluation and feasibility of synthetic MRI and a comparison with conventional double inversion recovery and fluid-attenuated inversion recovery sequences |
| title_sort | synthetic double inversion recovery imaging in brain mri quantitative evaluation and feasibility of synthetic mri and a comparison with conventional double inversion recovery and fluid attenuated inversion recovery sequences |
| topic | Magnetic resonance imaging Synthetic magnetic resonance imaging Double inversion recovery Inversion recovery |
| url | https://doi.org/10.1186/s12880-022-00877-4 |
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