Remimazolam in perioperative management of Eisenmenger syndrome: a case report

Abstract Background Eisenmenger syndrome (ES) is characterized by severe and irreversible pulmonary hypertension stemming from an uncorrected intracardiac shunt of significant size. The imbalance between systemic and pulmonary artery pressures predisposes patients with ES to the risk of cardiac arre...

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Main Authors: Kazuya Hashimoto, Tsuguhiro Matsumoto, Toshiyuki Mizota, Shinichi Kai, Moritoki Egi
Format: Article
Language:English
Published: SpringerOpen 2024-02-01
Series:JA Clinical Reports
Subjects:
Online Access:https://doi.org/10.1186/s40981-024-00692-6
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author Kazuya Hashimoto
Tsuguhiro Matsumoto
Toshiyuki Mizota
Shinichi Kai
Moritoki Egi
author_facet Kazuya Hashimoto
Tsuguhiro Matsumoto
Toshiyuki Mizota
Shinichi Kai
Moritoki Egi
author_sort Kazuya Hashimoto
collection DOAJ
description Abstract Background Eisenmenger syndrome (ES) is characterized by severe and irreversible pulmonary hypertension stemming from an uncorrected intracardiac shunt of significant size. The imbalance between systemic and pulmonary artery pressures predisposes patients with ES to the risk of cardiac arrest. Remimazolam has caused less circulatory depression, which may be advantageous for ES. However, no studies reported the use of remimazolam in perioperative ES management. Case presentation A 45-year-old female patient with ES derived from a ventricular septal defect was scheduled to undergo bilateral adnexectomy for an ovarian tumor. Her oxygen saturation was 80% with 3 L/min oxygen at rest, and her pulmonary and systemic flow ratio was 0.53. She underwent general anesthesia with remimazolam, and intraoperative hemodynamics was stable without hypotension or reduced oxygen saturation. Conclusions Our successful management of ovarian tumor surgery in a patient with ES using remimazolam reveals its potential effectiveness in perioperative care.
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spelling doaj.art-b1aab24bc5f24bd1b3c24842478cbdd12024-03-05T17:56:15ZengSpringerOpenJA Clinical Reports2363-90242024-02-011011410.1186/s40981-024-00692-6Remimazolam in perioperative management of Eisenmenger syndrome: a case reportKazuya Hashimoto0Tsuguhiro Matsumoto1Toshiyuki Mizota2Shinichi Kai3Moritoki Egi4Department of Anesthesia, Kyoto University HospitalDepartment of Anesthesia, Kyoto University HospitalDepartment of Anesthesia, Kyoto University HospitalDepartment of Anesthesia, Kyoto University HospitalDepartment of Anesthesia, Kyoto University HospitalAbstract Background Eisenmenger syndrome (ES) is characterized by severe and irreversible pulmonary hypertension stemming from an uncorrected intracardiac shunt of significant size. The imbalance between systemic and pulmonary artery pressures predisposes patients with ES to the risk of cardiac arrest. Remimazolam has caused less circulatory depression, which may be advantageous for ES. However, no studies reported the use of remimazolam in perioperative ES management. Case presentation A 45-year-old female patient with ES derived from a ventricular septal defect was scheduled to undergo bilateral adnexectomy for an ovarian tumor. Her oxygen saturation was 80% with 3 L/min oxygen at rest, and her pulmonary and systemic flow ratio was 0.53. She underwent general anesthesia with remimazolam, and intraoperative hemodynamics was stable without hypotension or reduced oxygen saturation. Conclusions Our successful management of ovarian tumor surgery in a patient with ES using remimazolam reveals its potential effectiveness in perioperative care.https://doi.org/10.1186/s40981-024-00692-6Eisenmenger syndromePulmonary hypertensionRemimazolam
spellingShingle Kazuya Hashimoto
Tsuguhiro Matsumoto
Toshiyuki Mizota
Shinichi Kai
Moritoki Egi
Remimazolam in perioperative management of Eisenmenger syndrome: a case report
JA Clinical Reports
Eisenmenger syndrome
Pulmonary hypertension
Remimazolam
title Remimazolam in perioperative management of Eisenmenger syndrome: a case report
title_full Remimazolam in perioperative management of Eisenmenger syndrome: a case report
title_fullStr Remimazolam in perioperative management of Eisenmenger syndrome: a case report
title_full_unstemmed Remimazolam in perioperative management of Eisenmenger syndrome: a case report
title_short Remimazolam in perioperative management of Eisenmenger syndrome: a case report
title_sort remimazolam in perioperative management of eisenmenger syndrome a case report
topic Eisenmenger syndrome
Pulmonary hypertension
Remimazolam
url https://doi.org/10.1186/s40981-024-00692-6
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