Exploring Matrix Metalloproteinases in Children’s Oral Health: Mechanisms, Implications and Therapeutic Insights

The oral cavity is recognised as a dynamic environment where various physiological processes are set in motion during the course of a child's development. These processes include significant events such as tooth eruption, gingival development, and tissue repair [1]. Within this intricately orch...

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Bibliographic Details
Main Authors: Swagata saha, Manju Raman Nair
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2024-02-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://www.jcdr.net/articles/PDF/19074/68574_CE[Ra1]_F(SS)_QC_Ref_Pat(AN_SS)_PF1(RI_DK)_PFA_NC(RI_KM)_PN(KM).pdf
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Summary:The oral cavity is recognised as a dynamic environment where various physiological processes are set in motion during the course of a child's development. These processes include significant events such as tooth eruption, gingival development, and tissue repair [1]. Within this intricately orchestrated scenario, Matrix Metalloproteinases (MMPs) are identified as pivotal participants [2]. MMPs comprise a family of enzymes that are widely acknowledged for their engagement in the degradation of the Extracellular Matrix (ECM) and the remodelling of tissues, both of which are fundamental processes in the maintenance of tissue homeostasis. Nevertheless, the equilibrium overseen by MMPs has the potential to be disrupted, thus giving rise to the possibility of oral diseases manifesting in paediatric patients.
ISSN:2249-782X
0973-709X