Effects of refractive errors on macular blood flow and retinal thickness in school-age children assessed by OCTA
AIM: To quantitatively analyze the macular area blood perfusion and retinal thickness of school-age children in each ametropia group by using OCT angiography technology, in order to evaluate the effect of the changes of refractive state on the macular area blood perfusion and retinal thickness durin...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Press of International Journal of Ophthalmology (IJO PRESS)
2020-08-01
|
| Series: | Guoji Yanke Zazhi |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/cn_publish/2020/8/202008031.pdf |
| _version_ | 1818302288579526656 |
|---|---|
| author | Na Li Yan-Hua Qi |
| author_facet | Na Li Yan-Hua Qi |
| author_sort | Na Li |
| collection | DOAJ |
| description | AIM: To quantitatively analyze the macular area blood perfusion and retinal thickness of school-age children in each ametropia group by using OCT angiography technology, in order to evaluate the effect of the changes of refractive state on the macular area blood perfusion and retinal thickness during the growth and development of school-age children.<p>METHODS: In this study, 174 eyes were randomly selected from school-age children who were treated in the ophthalmic clinic from July 2018 to March 2019. The superficial retinal capillary of vessel density(SCPVD), deep retinal capillary of vessel density(DCPVD), central retinal thickness(CRT)and average retinal thickness(ART)were quantitatively analyzed using by OCT angiography technology. Additionally, the correlation between blood vessel density in macular area and retinal thickness was analyzed.<p>RESULTS: After quantitatively analysis, compared with emmetropia group, the SCPVD value of the high myopia group was decreased(<i>P</i><0.001). The DCPVD value of the hyperopia group was increased(<i>P</i>=0.004). The ART value of high myopia group was decreased(<i>P</i><0.001).There was no significant difference in CRT values between the ametropia group and the emmetropia group(<i>P</i>>0.05). SCPVD was positively correlated with ART as an independent factor(<i>r</i>=0.274, <i>P</i><0.01).<p>CONCLUSION:In the process of refractive development, SCPVD of children with high myopia decreases and ART becomes thinner. Moreover, SCPVD can be an independent factor positively correlated with ART during the whole refractive development. This suggests that the retina of school-age children with high myopia has presented pathological changes. |
| first_indexed | 2024-12-13T05:36:32Z |
| format | Article |
| id | doaj.art-b1ae3beb05eb4036a8a1e659f5bbaf3b |
| institution | Directory Open Access Journal |
| issn | 1672-5123 1672-5123 |
| language | English |
| last_indexed | 2024-12-13T05:36:32Z |
| publishDate | 2020-08-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-b1ae3beb05eb4036a8a1e659f5bbaf3b2022-12-21T23:57:55ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232020-08-012081439144210.3980/j.issn.1672-5123.2020.8.31Effects of refractive errors on macular blood flow and retinal thickness in school-age children assessed by OCTANa Li0Yan-Hua Qi1Department of Ophthalmology, the Second Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, ChinaDepartment of Ophthalmology, the Second Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, ChinaAIM: To quantitatively analyze the macular area blood perfusion and retinal thickness of school-age children in each ametropia group by using OCT angiography technology, in order to evaluate the effect of the changes of refractive state on the macular area blood perfusion and retinal thickness during the growth and development of school-age children.<p>METHODS: In this study, 174 eyes were randomly selected from school-age children who were treated in the ophthalmic clinic from July 2018 to March 2019. The superficial retinal capillary of vessel density(SCPVD), deep retinal capillary of vessel density(DCPVD), central retinal thickness(CRT)and average retinal thickness(ART)were quantitatively analyzed using by OCT angiography technology. Additionally, the correlation between blood vessel density in macular area and retinal thickness was analyzed.<p>RESULTS: After quantitatively analysis, compared with emmetropia group, the SCPVD value of the high myopia group was decreased(<i>P</i><0.001). The DCPVD value of the hyperopia group was increased(<i>P</i>=0.004). The ART value of high myopia group was decreased(<i>P</i><0.001).There was no significant difference in CRT values between the ametropia group and the emmetropia group(<i>P</i>>0.05). SCPVD was positively correlated with ART as an independent factor(<i>r</i>=0.274, <i>P</i><0.01).<p>CONCLUSION:In the process of refractive development, SCPVD of children with high myopia decreases and ART becomes thinner. Moreover, SCPVD can be an independent factor positively correlated with ART during the whole refractive development. This suggests that the retina of school-age children with high myopia has presented pathological changes.http://ies.ijo.cn/cn_publish/2020/8/202008031.pdfthe school-age childrenametropiathe macular area blood perfusionretinal thickness |
| spellingShingle | Na Li Yan-Hua Qi Effects of refractive errors on macular blood flow and retinal thickness in school-age children assessed by OCTA Guoji Yanke Zazhi the school-age children ametropia the macular area blood perfusion retinal thickness |
| title | Effects of refractive errors on macular blood flow and retinal thickness in school-age children assessed by OCTA |
| title_full | Effects of refractive errors on macular blood flow and retinal thickness in school-age children assessed by OCTA |
| title_fullStr | Effects of refractive errors on macular blood flow and retinal thickness in school-age children assessed by OCTA |
| title_full_unstemmed | Effects of refractive errors on macular blood flow and retinal thickness in school-age children assessed by OCTA |
| title_short | Effects of refractive errors on macular blood flow and retinal thickness in school-age children assessed by OCTA |
| title_sort | effects of refractive errors on macular blood flow and retinal thickness in school age children assessed by octa |
| topic | the school-age children ametropia the macular area blood perfusion retinal thickness |
| url | http://ies.ijo.cn/cn_publish/2020/8/202008031.pdf |
| work_keys_str_mv | AT nali effectsofrefractiveerrorsonmacularbloodflowandretinalthicknessinschoolagechildrenassessedbyocta AT yanhuaqi effectsofrefractiveerrorsonmacularbloodflowandretinalthicknessinschoolagechildrenassessedbyocta |