Osteogenic growth peptide is a potent anti-inflammatory and bone preserving hormone via cannabinoid receptor type 2

Osteogenic growth peptide is a potent anti-inflammatory and bone preserving hormone via cannabinoid receptor type 2

The endocannabinoid system consists mainly of 2-arachidonoylglycerol and anandamide, as well as cannabinoid receptor type 1 and type 2 (CB2). Based on previous studies, we hypothesized that a circulating peptide previously identified as osteogenic growth peptide (OGP) maintains a bone-protective CB2...

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Bibliographic Details
Main Authors: Bitya Raphael-Mizrahi, Malka Attar-Namdar, Mukesh Chourasia, Maria G Cascio, Avital Shurki, Joseph Tam, Moshe Neuman, Neta Rimmerman, Zvi Vogel, Arie Shteyer, Roger G Pertwee, Andreas Zimmer, Natalya M Kogan, Itai Bab, Yankel Gabet
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-05-01
Series:eLife
Subjects:
osteogenic growth peptide
endocannabinoid
CB2
cannabinoid receptor
bone
immunoregulation
Online Access:https://elifesciences.org/articles/65834

Internet

https://elifesciences.org/articles/65834

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