Clinical and histological evaluation of concentrated growth factor membrane bandage after gingival depigmentation: A case series

Concentrated growth factor (CGF) is a newer form of autologous platelet concentrate with an extra fibrin matrix and more growth factors than that observed with platelet-rich fibrin, due to its different centrifugation process. This case series evaluates the early wound healing with CGF membrane as a...

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Main Authors: Gaurav Prabhakar Shetty, Chaitrali Hanumantrao Lakade, Dipika Kalyan Mitra, Silvia Victor Rodrigues
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Journal of Indian Society of Periodontology
Subjects:
Online Access:http://www.jisponline.com/article.asp?issn=0972-124X;year=2022;volume=26;issue=5;spage=501;epage=506;aulast=Shetty
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author Gaurav Prabhakar Shetty
Chaitrali Hanumantrao Lakade
Dipika Kalyan Mitra
Silvia Victor Rodrigues
author_facet Gaurav Prabhakar Shetty
Chaitrali Hanumantrao Lakade
Dipika Kalyan Mitra
Silvia Victor Rodrigues
author_sort Gaurav Prabhakar Shetty
collection DOAJ
description Concentrated growth factor (CGF) is a newer form of autologous platelet concentrate with an extra fibrin matrix and more growth factors than that observed with platelet-rich fibrin, due to its different centrifugation process. This case series evaluates the early wound healing with CGF membrane as a periodontal bandage after depigmentation. Three individuals were selected for a split-mouth study. After surgical depigmentation, the test site received CGF membrane. Both groups were covered by a periodontal pack. Participants were assessed on the 3rd and 5th days using a Visual Analog Scale and a Healing Index. Epithelization test was done with toluidine blue on the 5th day and tissue samples were taken for histological evaluation. The application of CGF membrane showed better healing and lesser inflammatory cells. Thus, a CGF membrane is helpful in protecting the raw wound region of depigmented sites, improving patient comfort, and for better healing.
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spelling doaj.art-b1b07344dc5647f19d8de552844573a62022-12-22T04:13:40ZengWolters Kluwer Medknow PublicationsJournal of Indian Society of Periodontology0972-124X2022-01-0126550150610.4103/jisp.jisp_405_21Clinical and histological evaluation of concentrated growth factor membrane bandage after gingival depigmentation: A case seriesGaurav Prabhakar ShettyChaitrali Hanumantrao LakadeDipika Kalyan MitraSilvia Victor RodriguesConcentrated growth factor (CGF) is a newer form of autologous platelet concentrate with an extra fibrin matrix and more growth factors than that observed with platelet-rich fibrin, due to its different centrifugation process. This case series evaluates the early wound healing with CGF membrane as a periodontal bandage after depigmentation. Three individuals were selected for a split-mouth study. After surgical depigmentation, the test site received CGF membrane. Both groups were covered by a periodontal pack. Participants were assessed on the 3rd and 5th days using a Visual Analog Scale and a Healing Index. Epithelization test was done with toluidine blue on the 5th day and tissue samples were taken for histological evaluation. The application of CGF membrane showed better healing and lesser inflammatory cells. Thus, a CGF membrane is helpful in protecting the raw wound region of depigmented sites, improving patient comfort, and for better healing.http://www.jisponline.com/article.asp?issn=0972-124X;year=2022;volume=26;issue=5;spage=501;epage=506;aulast=Shettyconcentrated growth factor bandageconcentrated growth factor membraneconcentrated growth factorgingival hyperpigmentationnoneugenol periodontal dressingwound healing
spellingShingle Gaurav Prabhakar Shetty
Chaitrali Hanumantrao Lakade
Dipika Kalyan Mitra
Silvia Victor Rodrigues
Clinical and histological evaluation of concentrated growth factor membrane bandage after gingival depigmentation: A case series
Journal of Indian Society of Periodontology
concentrated growth factor bandage
concentrated growth factor membrane
concentrated growth factor
gingival hyperpigmentation
noneugenol periodontal dressing
wound healing
title Clinical and histological evaluation of concentrated growth factor membrane bandage after gingival depigmentation: A case series
title_full Clinical and histological evaluation of concentrated growth factor membrane bandage after gingival depigmentation: A case series
title_fullStr Clinical and histological evaluation of concentrated growth factor membrane bandage after gingival depigmentation: A case series
title_full_unstemmed Clinical and histological evaluation of concentrated growth factor membrane bandage after gingival depigmentation: A case series
title_short Clinical and histological evaluation of concentrated growth factor membrane bandage after gingival depigmentation: A case series
title_sort clinical and histological evaluation of concentrated growth factor membrane bandage after gingival depigmentation a case series
topic concentrated growth factor bandage
concentrated growth factor membrane
concentrated growth factor
gingival hyperpigmentation
noneugenol periodontal dressing
wound healing
url http://www.jisponline.com/article.asp?issn=0972-124X;year=2022;volume=26;issue=5;spage=501;epage=506;aulast=Shetty
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