Droplet Digital PCR Improves IG-/TR-based MRD Risk Definition in Childhood B-cell Precursor Acute Lymphoblastic Leukemia

Droplet Digital PCR Improves IG-/TR-based MRD Risk Definition in Childhood B-cell Precursor Acute Lymphoblastic Leukemia

Minimal residual disease (MRD) is the most powerful prognostic factor in pediatric acute lymphoblastic leukemia (ALL). Real-time quantitative polymerase chain reaction (RQ-PCR) represents the gold standard for molecular MRD assessment and risk-based stratification of front-line treatment. In the pro...

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Bibliographic Details
Main Authors:	Irene Della Starza, Vittorio Nunes, Federica Lovisa, Daniela Silvestri, Marzia Cavalli, Andrea Garofalo, Mimma Campeggio, Lucia Anna De Novi, Roberta Soscia, Carlotta Oggioni, Lara Mussolin, Andrea Biondi, Anna Guarini, Maria Grazia Valsecchi, Valentino Conter, Alessandra Biffi, Giuseppe Basso, Robin Foà, Giovanni Cazzaniga
Format:	Article
Language:	English
Published:	Wiley 2021-03-01
Series:	HemaSphere
Online Access:	http://journals.lww.com/10.1097/HS9.0000000000000543

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