Lock-in Amplifier-Based Impedance Detection of Tissue Type Using a Monopolar Injection Needle

For successful intra-articular injection therapy, it is essential to accurately position the tip of the injection needle into the target joint area while administering the drug into the affected tissue. In this study, we investigated the feasibility of a monopolar injection needle and lock-in amplif...

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Main Authors: Junsub Kim, Muhammad Aitzaz Abbasi, Taehee Kim, Ki Deok Park, Sungbo Cho
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/19/21/4614
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author Junsub Kim
Muhammad Aitzaz Abbasi
Taehee Kim
Ki Deok Park
Sungbo Cho
author_facet Junsub Kim
Muhammad Aitzaz Abbasi
Taehee Kim
Ki Deok Park
Sungbo Cho
author_sort Junsub Kim
collection DOAJ
description For successful intra-articular injection therapy, it is essential to accurately position the tip of the injection needle into the target joint area while administering the drug into the affected tissue. In this study, we investigated the feasibility of a monopolar injection needle and lock-in amplifier (LIA)-based impedance measurement system for detecting the tissue type where the needle tip is located. After positioning the monopolar injection needle tip into the dermis, hypodermis, or muscle layer of pork tissue, the electrical impedance was measured in the frequency range of 10 Hz to 10 kHz. We observed a difference in the results based on the tissue type where the needle was positioned (<i>p</i>-value &lt; 0.01). Therefore, the monopolar injection needle with electrical impedance measurement can be used to improve intra-articular injection therapy through non-destructive and real-time monitoring of the needle position in the tissues.
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spelling doaj.art-b1bba57548ab4b27874d3c5eabeb9b0d2022-12-22T02:52:42ZengMDPI AGSensors1424-82202019-10-011921461410.3390/s19214614s19214614Lock-in Amplifier-Based Impedance Detection of Tissue Type Using a Monopolar Injection NeedleJunsub Kim0Muhammad Aitzaz Abbasi1Taehee Kim2Ki Deok Park3Sungbo Cho4Gachon Advanced Institute for Health Science &amp; Technology, Gachon University, Incheon 21999, KoreaDepartment of Electronic Engineering, Gachon University, 1342 Seongnamdaero, Seongnam-si, Gyeonggi-do 13120, KoreaDepartment of Rehabilitation Medicine, Konkuk University Chungju Hospital, Chungju 27376, KoreaDepartment of Rehabilitation Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon 21565, KoreaGachon Advanced Institute for Health Science &amp; Technology, Gachon University, Incheon 21999, KoreaFor successful intra-articular injection therapy, it is essential to accurately position the tip of the injection needle into the target joint area while administering the drug into the affected tissue. In this study, we investigated the feasibility of a monopolar injection needle and lock-in amplifier (LIA)-based impedance measurement system for detecting the tissue type where the needle tip is located. After positioning the monopolar injection needle tip into the dermis, hypodermis, or muscle layer of pork tissue, the electrical impedance was measured in the frequency range of 10 Hz to 10 kHz. We observed a difference in the results based on the tissue type where the needle was positioned (<i>p</i>-value &lt; 0.01). Therefore, the monopolar injection needle with electrical impedance measurement can be used to improve intra-articular injection therapy through non-destructive and real-time monitoring of the needle position in the tissues.https://www.mdpi.com/1424-8220/19/21/4614bio-impedanceintra-articular injection therapylock-in amplifiermonopolar injection needleporcine tissue
spellingShingle Junsub Kim
Muhammad Aitzaz Abbasi
Taehee Kim
Ki Deok Park
Sungbo Cho
Lock-in Amplifier-Based Impedance Detection of Tissue Type Using a Monopolar Injection Needle
Sensors
bio-impedance
intra-articular injection therapy
lock-in amplifier
monopolar injection needle
porcine tissue
title Lock-in Amplifier-Based Impedance Detection of Tissue Type Using a Monopolar Injection Needle
title_full Lock-in Amplifier-Based Impedance Detection of Tissue Type Using a Monopolar Injection Needle
title_fullStr Lock-in Amplifier-Based Impedance Detection of Tissue Type Using a Monopolar Injection Needle
title_full_unstemmed Lock-in Amplifier-Based Impedance Detection of Tissue Type Using a Monopolar Injection Needle
title_short Lock-in Amplifier-Based Impedance Detection of Tissue Type Using a Monopolar Injection Needle
title_sort lock in amplifier based impedance detection of tissue type using a monopolar injection needle
topic bio-impedance
intra-articular injection therapy
lock-in amplifier
monopolar injection needle
porcine tissue
url https://www.mdpi.com/1424-8220/19/21/4614
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