Nrf2-mediated activation of HO-1 is required in the blocking effect of compound K, a ginseng saponin metabolite, against oxidative stress damage in ARPE-19 human retinal pigment epithelial cells
Background: The beneficial effects of compound K (CK) on different chronic diseases have been shown to be at least related to antioxidant action. Nevertheless, since its antioxidant activity in human retinal pigment epithelial (RPE) cells is still unknown, here we investigated whether CK alleviates...
Main Authors: | Cheol Park, Hee-Jae Cha, Kyoung-Seob Song, Heui-Soo Kim, EunJin Bang, Hyesook Lee, Cheng-Yun Jin, Gi-Young Kim, Yung Hyun Choi |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-03-01
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Series: | Journal of Ginseng Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1226845322001233 |
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