Mechanisms of U87 astrocytoma cell uptake and trafficking of monomeric versus protofibril Alzheimer's disease amyloid-β proteins.

A significant hallmark of Alzheimer's disease is the formation of senile plaques in the brain due to the unbalanced levels of amyloid-beta (Aβ). However, although how Aβ is produced from amyloid precursor proteins is well understood, little is known regarding the clearance and metabolism of var...

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Príomhchruthaitheoirí: Yali Li, Deshu Cheng, Ran Cheng, Xinyu Zhu, Tao Wan, Jianmiao Liu, Rongying Zhang
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Public Library of Science (PLoS) 2014-01-01
Sraith:PLoS ONE
Rochtain ar líne:http://europepmc.org/articles/PMC4062444?pdf=render