The intratumour microbiota and neutrophilic inflammation in squamous cell vulvar carcinoma microenvironment

The intratumour microbiota and neutrophilic inflammation in squamous cell vulvar carcinoma microenvironment

Abstract Background A causal link between microbiota composition (dysbiosis) and oncogenesis has been demonstrated for several types of cancer. Neutrophils play a role in both immune protection against bacterial threats and carcinogenesis. This study aimed to characterise intratumoral bacteria in vu...

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Main Authors: Natalia Rustetska, Magdalena Szczepaniak, Krzysztof Goryca, Elwira Bakuła-Zalewska, Małgorzata Figat, Artur Kowalik, Stanisław Góźdź, Magdalena Kowalewska
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Journal of Translational Medicine
Subjects:
Vulvar carcinoma
Microbiota
Fusobacterium nucleatum
Pseudomonas aeruginosa
Neutrophil serine protease
Microabscess
Online Access:https://doi.org/10.1186/s12967-023-04113-7

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