Antinociception synergy between the peripheral and spinal sites of the heme oxygenase-carbon monoxide pathway

Antinociception synergy between the peripheral and spinal sites of the heme oxygenase-carbon monoxide pathway

We have shown that the peripheral and spinal cord heme oxygenase (HO)-carbon monoxide (CO)-soluble guanylate cyclase-cGMP pathways play an important role in antinociception in the rat experimental formalin model. Our objective was to determine if there is synergism between peripheral (paw) and spina...

Full description

Bibliographic Details
Main Authors: C.G.O. Nascimento, L.G.S. Branco
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2009-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Nociception
Carbon monoxide
Formalin
Hypernociception
Antinociception
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000100020

Similar Items

Similar Items