Potential Alternative Therapeutic Modalities for Management Head and Neck Squamous Cell Carcinoma: A Review

Head and neck squamous cell carcinoma (HNSCC) includes malignancies of the lip and oral cavity, oropharynx, nasopharynx, larynx, and hypopharynx. It is among the most common malignancy worldwide, affecting nearly 1 million people annually. The traditional treatment options for HNSCC include surgery,...

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Main Authors: Keihan Afshari, Karpal Singh Sohal
Format: Article
Language:English
Published: SAGE Publishing 2023-06-01
Series:Cancer Control
Online Access:https://doi.org/10.1177/10732748231185003
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author Keihan Afshari
Karpal Singh Sohal
author_facet Keihan Afshari
Karpal Singh Sohal
author_sort Keihan Afshari
collection DOAJ
description Head and neck squamous cell carcinoma (HNSCC) includes malignancies of the lip and oral cavity, oropharynx, nasopharynx, larynx, and hypopharynx. It is among the most common malignancy worldwide, affecting nearly 1 million people annually. The traditional treatment options for HNSCC include surgery, radiotherapy, and conventional chemotherapy. However, these treatment options have their specific sequelae, which produce high rates of recurrence and severe treatment-related disabilities. Recent technological advancements have led to tremendous progress in understanding tumor biology, and hence the emergence of several alternative therapeutic modalities for managing cancers (including HNSCC). These treatment options are stem cell targeted therapy, gene therapy, and immunotherapy. Therefore, this review article aims to provide an overview of these alternative treatments of HNSCC.
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spelling doaj.art-b1c34409ac7c48219d567e5a78e259212023-09-12T13:35:36ZengSAGE PublishingCancer Control1526-23592023-06-013010.1177/10732748231185003Potential Alternative Therapeutic Modalities for Management Head and Neck Squamous Cell Carcinoma: A ReviewKeihan AfshariKarpal Singh SohalHead and neck squamous cell carcinoma (HNSCC) includes malignancies of the lip and oral cavity, oropharynx, nasopharynx, larynx, and hypopharynx. It is among the most common malignancy worldwide, affecting nearly 1 million people annually. The traditional treatment options for HNSCC include surgery, radiotherapy, and conventional chemotherapy. However, these treatment options have their specific sequelae, which produce high rates of recurrence and severe treatment-related disabilities. Recent technological advancements have led to tremendous progress in understanding tumor biology, and hence the emergence of several alternative therapeutic modalities for managing cancers (including HNSCC). These treatment options are stem cell targeted therapy, gene therapy, and immunotherapy. Therefore, this review article aims to provide an overview of these alternative treatments of HNSCC.https://doi.org/10.1177/10732748231185003
spellingShingle Keihan Afshari
Karpal Singh Sohal
Potential Alternative Therapeutic Modalities for Management Head and Neck Squamous Cell Carcinoma: A Review
Cancer Control
title Potential Alternative Therapeutic Modalities for Management Head and Neck Squamous Cell Carcinoma: A Review
title_full Potential Alternative Therapeutic Modalities for Management Head and Neck Squamous Cell Carcinoma: A Review
title_fullStr Potential Alternative Therapeutic Modalities for Management Head and Neck Squamous Cell Carcinoma: A Review
title_full_unstemmed Potential Alternative Therapeutic Modalities for Management Head and Neck Squamous Cell Carcinoma: A Review
title_short Potential Alternative Therapeutic Modalities for Management Head and Neck Squamous Cell Carcinoma: A Review
title_sort potential alternative therapeutic modalities for management head and neck squamous cell carcinoma a review
url https://doi.org/10.1177/10732748231185003
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