Intercellular communication atlas reveals Oprm1 as a neuroprotective factor for retinal ganglion cells
Abstract Previous studies of neuronal survival have primarily focused on identifying intrinsic mechanisms controlling the process. This study explored how intercellular communication contributes to retinal ganglion cell (RGC) survival following optic nerve crush based on single-cell RNA-seq analysis...
Main Authors: | Cheng Qian, Ying Xin, Cheng Qi, Hui Wang, Bryan C. Dong, Donald J. Zack, Seth Blackshaw, Samer Hattar, Feng-Quan Zhou, Jiang Qian |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-03-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-46428-z |
Similar Items
-
Single-Cell Profiles of Retinal Ganglion Cells Differing in Resilience to Injury Reveal Neuroprotective Genes
by: Tran, Nicholas M, et al.
Published: (2021) -
p58IPK Is an Endogenous Neuroprotectant for Retinal Ganglion Cells
by: Todd McLaughlin, et al.
Published: (2018-09-01) -
Neuroprotection of the rat’s retinal ganglion cells against glutamate-induced toxicity
by: Kariman M.A El-Gohari, et al.
Published: (2016-01-01) -
The Role of Endogenous Neuroprotective Mechanisms in the Prevention of Retinal Ganglion Cells Degeneration
by: Marita Pietrucha-Dutczak, et al.
Published: (2018-11-01) -
Cell-Based Neuroprotection of Retinal Ganglion Cells in Animal Models of Optic Neuropathies
by: Yue Hu, et al.
Published: (2021-11-01)