Trends in the Tissue Culture Techniques and the Synthesis of Bioactive Compounds in <i>Eurycoma longifolia</i> Jack—Current Status and Future Perspectives

Over the last two decades, there has been a concerted effort by researchers to mass propagate <i>Eurycoma longifolia</i> and improve the yield of its very important and sought-after anti-cancer and aphrodisiac bioactive compounds. To achieve this, various techniques have been used to mas...

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Main Authors: Sani Sale, Sreeramanan Subramaniam, Mohamad Fadhli Mad’ Atari
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Plants
Subjects:
Online Access:https://www.mdpi.com/2223-7747/13/1/107
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author Sani Sale
Sreeramanan Subramaniam
Mohamad Fadhli Mad’ Atari
author_facet Sani Sale
Sreeramanan Subramaniam
Mohamad Fadhli Mad’ Atari
author_sort Sani Sale
collection DOAJ
description Over the last two decades, there has been a concerted effort by researchers to mass propagate <i>Eurycoma longifolia</i> and improve the yield of its very important and sought-after anti-cancer and aphrodisiac bioactive compounds. To achieve this, various techniques have been used to mass propagate and improve the yield of these bioactive compounds in tissue cultures. These techniques include the optimization of media conditions and application of various types and combinations of plant growth regulators (PGRs). In addition, some elicitation techniques have been used to improve the synthesis of these bioactive compounds. However, in comparison with other herbal species with similar economic importance, many techniques have not been applied to <i>E. longifolia</i>. Adopting the most recent methodologies would ensure efficiency and sustainability in the in vitro production of bioactive compounds in <i>E. longifolia</i>. Therefore, in this review, we present an up-to-date record on the success stories in the tissue culture techniques and synthesis of bioactive compounds. In addition, we attempted to identify some of the missing links on the road to the effective and sustainable biotechnological utilization of this super important biological resource.
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spelling doaj.art-b1ce090ad3af4748ba2695d77d484f802024-01-10T15:06:18ZengMDPI AGPlants2223-77472023-12-0113110710.3390/plants13010107Trends in the Tissue Culture Techniques and the Synthesis of Bioactive Compounds in <i>Eurycoma longifolia</i> Jack—Current Status and Future PerspectivesSani Sale0Sreeramanan Subramaniam1Mohamad Fadhli Mad’ Atari2School of Biological Sciences, Universiti Sains Malaysia (USM), Georgetown 11800, Penang, MalaysiaSchool of Biological Sciences, Universiti Sains Malaysia (USM), Georgetown 11800, Penang, MalaysiaSchool of Biological Sciences, Universiti Sains Malaysia (USM), Georgetown 11800, Penang, MalaysiaOver the last two decades, there has been a concerted effort by researchers to mass propagate <i>Eurycoma longifolia</i> and improve the yield of its very important and sought-after anti-cancer and aphrodisiac bioactive compounds. To achieve this, various techniques have been used to mass propagate and improve the yield of these bioactive compounds in tissue cultures. These techniques include the optimization of media conditions and application of various types and combinations of plant growth regulators (PGRs). In addition, some elicitation techniques have been used to improve the synthesis of these bioactive compounds. However, in comparison with other herbal species with similar economic importance, many techniques have not been applied to <i>E. longifolia</i>. Adopting the most recent methodologies would ensure efficiency and sustainability in the in vitro production of bioactive compounds in <i>E. longifolia</i>. Therefore, in this review, we present an up-to-date record on the success stories in the tissue culture techniques and synthesis of bioactive compounds. In addition, we attempted to identify some of the missing links on the road to the effective and sustainable biotechnological utilization of this super important biological resource.https://www.mdpi.com/2223-7747/13/1/107<i>Eurycoma longifolia</i>plant tissue cultureelicitationbiosynthesisbioactive compounds
spellingShingle Sani Sale
Sreeramanan Subramaniam
Mohamad Fadhli Mad’ Atari
Trends in the Tissue Culture Techniques and the Synthesis of Bioactive Compounds in <i>Eurycoma longifolia</i> Jack—Current Status and Future Perspectives
Plants
<i>Eurycoma longifolia</i>
plant tissue culture
elicitation
biosynthesis
bioactive compounds
title Trends in the Tissue Culture Techniques and the Synthesis of Bioactive Compounds in <i>Eurycoma longifolia</i> Jack—Current Status and Future Perspectives
title_full Trends in the Tissue Culture Techniques and the Synthesis of Bioactive Compounds in <i>Eurycoma longifolia</i> Jack—Current Status and Future Perspectives
title_fullStr Trends in the Tissue Culture Techniques and the Synthesis of Bioactive Compounds in <i>Eurycoma longifolia</i> Jack—Current Status and Future Perspectives
title_full_unstemmed Trends in the Tissue Culture Techniques and the Synthesis of Bioactive Compounds in <i>Eurycoma longifolia</i> Jack—Current Status and Future Perspectives
title_short Trends in the Tissue Culture Techniques and the Synthesis of Bioactive Compounds in <i>Eurycoma longifolia</i> Jack—Current Status and Future Perspectives
title_sort trends in the tissue culture techniques and the synthesis of bioactive compounds in i eurycoma longifolia i jack current status and future perspectives
topic <i>Eurycoma longifolia</i>
plant tissue culture
elicitation
biosynthesis
bioactive compounds
url https://www.mdpi.com/2223-7747/13/1/107
work_keys_str_mv AT sanisale trendsinthetissueculturetechniquesandthesynthesisofbioactivecompoundsinieurycomalongifoliaijackcurrentstatusandfutureperspectives
AT sreeramanansubramaniam trendsinthetissueculturetechniquesandthesynthesisofbioactivecompoundsinieurycomalongifoliaijackcurrentstatusandfutureperspectives
AT mohamadfadhlimadatari trendsinthetissueculturetechniquesandthesynthesisofbioactivecompoundsinieurycomalongifoliaijackcurrentstatusandfutureperspectives