Prevalence of hearing loss, tinnitus, vertigo and sudden deafness among patients with polymyositis and dermatomyositis
Abstract Little is known about a possible association of autoimmune inner ear disease among patients diagnosed with polymyositis (PM)/dermatomyositis (DM). This study aimed to explore differences in the prevalence of inner ear symptoms among patients with and without PM/DM using a nationwide populat...
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Nature Portfolio
2024-03-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-024-56372-z |
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| author | Shih-Han Hung Sudha Xirasagar Luong Huu Dang Nguyen-Kieu Viet-Nhi Yen-Fu Cheng Chin-Shyan Chen Herng-Ching Lin |
| author_facet | Shih-Han Hung Sudha Xirasagar Luong Huu Dang Nguyen-Kieu Viet-Nhi Yen-Fu Cheng Chin-Shyan Chen Herng-Ching Lin |
| author_sort | Shih-Han Hung |
| collection | DOAJ |
| description | Abstract Little is known about a possible association of autoimmune inner ear disease among patients diagnosed with polymyositis (PM)/dermatomyositis (DM). This study aimed to explore differences in the prevalence of inner ear symptoms among patients with and without PM/DM using a nationwide population-based dataset. Data for this study were retrieved from the Taiwan National Health Insurance Research Database. The study sample included 1622 patients diagnosed with PM/DM and 8109 propensity-score matched comparison patients without PM/DM. We performed multivariate logistic regressions to calculate odds ratios (ORs) and 95% confidence interval (CI) for tinnitus, hearing loss, sudden deafness, and vertigo among patients with PM/DM versus comparison patients. Chi-square tests showed statistically significant differences between patients with PM/DM and comparison patients in the prevalence of tinnitus (16.1% vs. 12.7%, p < 0.001), non-conductive hearing loss (9.2% vs. 6.8%, p < 0.001), and vertigo (14.4% vs. 11.1%, p < 0.001). The adjusted ORs for tinnitus, non-conductive hearing loss, and vertigo, respectively, were 1.332 (95% CI = 1.147–1.547), 1.399 (95% CI = 1.154–1.696), and 1.374 (95% CI = 1.173–1.611) for patients with PM/DM when compared to comparison patients. Our study finds that patients with PM/DM have higher prevalence rates of tinnitus, non-conductive hearing loss, and vertigo than comparison patients. |
| first_indexed | 2024-04-25T01:07:24Z |
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| language | English |
| last_indexed | 2024-04-25T01:07:24Z |
| publishDate | 2024-03-01 |
| publisher | Nature Portfolio |
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| series | Scientific Reports |
| spelling | doaj.art-b1cf9779db344694879038a98565834f2024-03-10T12:11:40ZengNature PortfolioScientific Reports2045-23222024-03-011411710.1038/s41598-024-56372-zPrevalence of hearing loss, tinnitus, vertigo and sudden deafness among patients with polymyositis and dermatomyositisShih-Han Hung0Sudha Xirasagar1Luong Huu Dang2Nguyen-Kieu Viet-Nhi3Yen-Fu Cheng4Chin-Shyan Chen5Herng-Ching Lin6Department of Otolaryngology, School of Medicine, Taipei Medical UniversityDepartment of Health Services Policy and Management, Arnold School of Public Health, University of South CarolinaDepartment of Otolaryngology, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh CityInternational Ph.D. Program in Medicine, College of Medicine, Taipei Medical UniversityDepartment of Medical Research, Taipei Veterans General HospitalDepartment of Economics, National Taipei UniversitySchool of Health Care Administration, College of Management, Taipei Medical UniversityAbstract Little is known about a possible association of autoimmune inner ear disease among patients diagnosed with polymyositis (PM)/dermatomyositis (DM). This study aimed to explore differences in the prevalence of inner ear symptoms among patients with and without PM/DM using a nationwide population-based dataset. Data for this study were retrieved from the Taiwan National Health Insurance Research Database. The study sample included 1622 patients diagnosed with PM/DM and 8109 propensity-score matched comparison patients without PM/DM. We performed multivariate logistic regressions to calculate odds ratios (ORs) and 95% confidence interval (CI) for tinnitus, hearing loss, sudden deafness, and vertigo among patients with PM/DM versus comparison patients. Chi-square tests showed statistically significant differences between patients with PM/DM and comparison patients in the prevalence of tinnitus (16.1% vs. 12.7%, p < 0.001), non-conductive hearing loss (9.2% vs. 6.8%, p < 0.001), and vertigo (14.4% vs. 11.1%, p < 0.001). The adjusted ORs for tinnitus, non-conductive hearing loss, and vertigo, respectively, were 1.332 (95% CI = 1.147–1.547), 1.399 (95% CI = 1.154–1.696), and 1.374 (95% CI = 1.173–1.611) for patients with PM/DM when compared to comparison patients. Our study finds that patients with PM/DM have higher prevalence rates of tinnitus, non-conductive hearing loss, and vertigo than comparison patients.https://doi.org/10.1038/s41598-024-56372-zTinnitusPolymyositisDermatomyositisInner ear disordersEpidemiology |
| spellingShingle | Shih-Han Hung Sudha Xirasagar Luong Huu Dang Nguyen-Kieu Viet-Nhi Yen-Fu Cheng Chin-Shyan Chen Herng-Ching Lin Prevalence of hearing loss, tinnitus, vertigo and sudden deafness among patients with polymyositis and dermatomyositis Scientific Reports Tinnitus Polymyositis Dermatomyositis Inner ear disorders Epidemiology |
| title | Prevalence of hearing loss, tinnitus, vertigo and sudden deafness among patients with polymyositis and dermatomyositis |
| title_full | Prevalence of hearing loss, tinnitus, vertigo and sudden deafness among patients with polymyositis and dermatomyositis |
| title_fullStr | Prevalence of hearing loss, tinnitus, vertigo and sudden deafness among patients with polymyositis and dermatomyositis |
| title_full_unstemmed | Prevalence of hearing loss, tinnitus, vertigo and sudden deafness among patients with polymyositis and dermatomyositis |
| title_short | Prevalence of hearing loss, tinnitus, vertigo and sudden deafness among patients with polymyositis and dermatomyositis |
| title_sort | prevalence of hearing loss tinnitus vertigo and sudden deafness among patients with polymyositis and dermatomyositis |
| topic | Tinnitus Polymyositis Dermatomyositis Inner ear disorders Epidemiology |
| url | https://doi.org/10.1038/s41598-024-56372-z |
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