Spontaneous tumor regression
Spontaneous tumor regression is defined as spontaneous remission or disappearance of a tumor in the absence of any treatment. Activation of immune system has been found important in its pathogenesis. Further, spontaneous tumor regression appears to be associated with apoptosis, tumor microenvironmen...
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Format: | Article |
Language: | English |
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Turkiye Klinikleri
2016-04-01
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Series: | Journal of Oncological Sciences |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2452336416300255 |
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author | Tarik Salman |
author_facet | Tarik Salman |
author_sort | Tarik Salman |
collection | DOAJ |
description | Spontaneous tumor regression is defined as spontaneous remission or disappearance of a tumor in the absence of any treatment. Activation of immune system has been found important in its pathogenesis. Further, spontaneous tumor regression appears to be associated with apoptosis, tumor microenvironment, and DNA oncogenic suppression. It can be observed in all types of tumors, most frequently in renal cell cancer, germ cell tumors, malignant melanoma, and neuroblastoma. It is crucial to understand this phenomenon in order to improve the immune treatments which are effective in neoplastic diseases. |
first_indexed | 2024-04-10T10:37:58Z |
format | Article |
id | doaj.art-b1d1eafca1df4f7db61a19d9cec112bf |
institution | Directory Open Access Journal |
issn | 2452-3364 |
language | English |
last_indexed | 2024-04-10T10:37:58Z |
publishDate | 2016-04-01 |
publisher | Turkiye Klinikleri |
record_format | Article |
series | Journal of Oncological Sciences |
spelling | doaj.art-b1d1eafca1df4f7db61a19d9cec112bf2023-02-15T16:20:45ZengTurkiye KlinikleriJournal of Oncological Sciences2452-33642016-04-01211410.1016/j.jons.2016.04.008Spontaneous tumor regressionTarik SalmanSpontaneous tumor regression is defined as spontaneous remission or disappearance of a tumor in the absence of any treatment. Activation of immune system has been found important in its pathogenesis. Further, spontaneous tumor regression appears to be associated with apoptosis, tumor microenvironment, and DNA oncogenic suppression. It can be observed in all types of tumors, most frequently in renal cell cancer, germ cell tumors, malignant melanoma, and neuroblastoma. It is crucial to understand this phenomenon in order to improve the immune treatments which are effective in neoplastic diseases.http://www.sciencedirect.com/science/article/pii/S2452336416300255Tumor regressionInflammatory responseMicroenvironment |
spellingShingle | Tarik Salman Spontaneous tumor regression Journal of Oncological Sciences Tumor regression Inflammatory response Microenvironment |
title | Spontaneous tumor regression |
title_full | Spontaneous tumor regression |
title_fullStr | Spontaneous tumor regression |
title_full_unstemmed | Spontaneous tumor regression |
title_short | Spontaneous tumor regression |
title_sort | spontaneous tumor regression |
topic | Tumor regression Inflammatory response Microenvironment |
url | http://www.sciencedirect.com/science/article/pii/S2452336416300255 |
work_keys_str_mv | AT tariksalman spontaneoustumorregression |