Indications and Findings of Upper Endoscopies in Males and Females, Are They the Same or Different?

Sex and gender can affect the prevalence and prognosis of diseases. Our aim was to assess similarities and differences for males and females who underwent an upper endoscopy, with regards to indications and results. We reviewed all upper endoscopy reports from 2012 to 2016. Data regarding demographi...

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Main Authors: Naim Abu-Freha, Roni Gat, Aerin Philip, Baha Yousef, Liza Ben Shoshan, David Yardeni, Anat Nevo-Shor, Victor Novack, Ohad Etzion
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/10/8/1620
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author Naim Abu-Freha
Roni Gat
Aerin Philip
Baha Yousef
Liza Ben Shoshan
David Yardeni
Anat Nevo-Shor
Victor Novack
Ohad Etzion
author_facet Naim Abu-Freha
Roni Gat
Aerin Philip
Baha Yousef
Liza Ben Shoshan
David Yardeni
Anat Nevo-Shor
Victor Novack
Ohad Etzion
author_sort Naim Abu-Freha
collection DOAJ
description Sex and gender can affect the prevalence and prognosis of diseases. Our aim was to assess similarities and differences for males and females who underwent an upper endoscopy, with regards to indications and results. We reviewed all upper endoscopy reports from 2012 to 2016. Data regarding demographics, indications, and procedure findings were collected. The upper endoscopy findings were compared regarding the most common indications: gastroesophageal reflux, abdominal pain, gastrointestinal bleeding, and anemia. We investigated 12,213 gastroscopies among males (age, 56.7 ± 17.4) and 15,817 among females (age, 56.0 ± 17.3, <i>p</i> = 0.002). Males who underwent an upper endoscopy for gastroesophageal reflux had higher rates of esophagitis (7.7% vs. 3.4%, <i>p</i> < 0.001) and Barret’s esophagus (4.4% vs. 1.5%, <i>p</i> < 0.001). Females who underwent an upper endoscopy for abdominal pain had a higher rate of hiatal hernia, whereas males had higher rates of esophagitis, helicobacter pylori infection, gastritis, gastric ulcer, duodenitis, and duodenal ulcer (<i>p</i> < 0.001). Gastrointestinal bleeding as an indication for upper endoscopy showed that helicobacter, duodenitis, and duodenal ulcers are more common among males compared to females (<i>p</i> < 0.001). Males with anemia who underwent an upper endoscopy had higher rates of esophagitis (<i>p</i> = 0.021) gastritis (<i>p</i> = 0.002), duodenitis (<i>p</i> < 0.001), and duodenal ulcer (<i>p</i> < 0.001). We found significant differences regarding the pathological gastroscopy findings between males and females in relation to the different indications.
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spelling doaj.art-b1d3e5fd74534738a682e463a513de152023-11-21T15:05:01ZengMDPI AGJournal of Clinical Medicine2077-03832021-04-01108162010.3390/jcm10081620Indications and Findings of Upper Endoscopies in Males and Females, Are They the Same or Different?Naim Abu-Freha0Roni Gat1Aerin Philip2Baha Yousef3Liza Ben Shoshan4David Yardeni5Anat Nevo-Shor6Victor Novack7Ohad Etzion8Soroka University Medical Center, Faculty of Health Sciences, The Institute of Gastroenterology and Hepatology, Ben-Gurion University of the Negev, Beer-Sheva 84101, IsraelSoroka Clinical Research Center, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 84010, IsraelFaculty of Health Sciences, Medical School for International Health, Ben-Gurion University of the Negev, Beer-Sheva 84101, IsraelSoroka University Medical Center, Faculty of Health Sciences, The Institute of Gastroenterology and Hepatology, Ben-Gurion University of the Negev, Beer-Sheva 84101, IsraelSoroka University Medical Center, Faculty of Health Sciences, The Institute of Gastroenterology and Hepatology, Ben-Gurion University of the Negev, Beer-Sheva 84101, IsraelSoroka University Medical Center, Faculty of Health Sciences, The Institute of Gastroenterology and Hepatology, Ben-Gurion University of the Negev, Beer-Sheva 84101, IsraelSoroka University Medical Center, Faculty of Health Sciences, The Institute of Gastroenterology and Hepatology, Ben-Gurion University of the Negev, Beer-Sheva 84101, IsraelSoroka Clinical Research Center, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 84010, IsraelSoroka University Medical Center, Faculty of Health Sciences, The Institute of Gastroenterology and Hepatology, Ben-Gurion University of the Negev, Beer-Sheva 84101, IsraelSex and gender can affect the prevalence and prognosis of diseases. Our aim was to assess similarities and differences for males and females who underwent an upper endoscopy, with regards to indications and results. We reviewed all upper endoscopy reports from 2012 to 2016. Data regarding demographics, indications, and procedure findings were collected. The upper endoscopy findings were compared regarding the most common indications: gastroesophageal reflux, abdominal pain, gastrointestinal bleeding, and anemia. We investigated 12,213 gastroscopies among males (age, 56.7 ± 17.4) and 15,817 among females (age, 56.0 ± 17.3, <i>p</i> = 0.002). Males who underwent an upper endoscopy for gastroesophageal reflux had higher rates of esophagitis (7.7% vs. 3.4%, <i>p</i> < 0.001) and Barret’s esophagus (4.4% vs. 1.5%, <i>p</i> < 0.001). Females who underwent an upper endoscopy for abdominal pain had a higher rate of hiatal hernia, whereas males had higher rates of esophagitis, helicobacter pylori infection, gastritis, gastric ulcer, duodenitis, and duodenal ulcer (<i>p</i> < 0.001). Gastrointestinal bleeding as an indication for upper endoscopy showed that helicobacter, duodenitis, and duodenal ulcers are more common among males compared to females (<i>p</i> < 0.001). Males with anemia who underwent an upper endoscopy had higher rates of esophagitis (<i>p</i> = 0.021) gastritis (<i>p</i> = 0.002), duodenitis (<i>p</i> < 0.001), and duodenal ulcer (<i>p</i> < 0.001). We found significant differences regarding the pathological gastroscopy findings between males and females in relation to the different indications.https://www.mdpi.com/2077-0383/10/8/1620upper endoscopymalesfemalesindicationfindings
spellingShingle Naim Abu-Freha
Roni Gat
Aerin Philip
Baha Yousef
Liza Ben Shoshan
David Yardeni
Anat Nevo-Shor
Victor Novack
Ohad Etzion
Indications and Findings of Upper Endoscopies in Males and Females, Are They the Same or Different?
Journal of Clinical Medicine
upper endoscopy
males
females
indication
findings
title Indications and Findings of Upper Endoscopies in Males and Females, Are They the Same or Different?
title_full Indications and Findings of Upper Endoscopies in Males and Females, Are They the Same or Different?
title_fullStr Indications and Findings of Upper Endoscopies in Males and Females, Are They the Same or Different?
title_full_unstemmed Indications and Findings of Upper Endoscopies in Males and Females, Are They the Same or Different?
title_short Indications and Findings of Upper Endoscopies in Males and Females, Are They the Same or Different?
title_sort indications and findings of upper endoscopies in males and females are they the same or different
topic upper endoscopy
males
females
indication
findings
url https://www.mdpi.com/2077-0383/10/8/1620
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