Neonatal Alloimmune Thrombocytopenia Detected After Traumatic Delivery: Case Report
Neonatal Alloimmune Thrombocytopenia (NAIT), a complication of maternal alloimmunization against fetal platelets, is the result of immune destruction of platelets due to maternal antibodies in the early period. The cause of thrombocytopenia here is by antibodies developed against human platelet anti...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2021-08-01
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| Series: | Forbes Tıp Dergisi |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=forbes&un=FJM-14632 |
| _version_ | 1797767548466364416 |
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| author | Gökhan Kaya Sema Tanriverdi |
| author_facet | Gökhan Kaya Sema Tanriverdi |
| author_sort | Gökhan Kaya |
| collection | DOAJ |
| description | Neonatal Alloimmune Thrombocytopenia (NAIT), a complication of maternal alloimmunization against fetal platelets, is the result of immune destruction of platelets due to maternal antibodies in the early period. The cause of thrombocytopenia here is by antibodies developed against human platelet antigens frequently inherited from the mother. The clinical manifestations of NAIT extend from asymptomatic to severe bleeding. Platelet suspension can be used in the setting of severe thrombocytopenia or life-threatening bleeding. High-dose intravenous immunoglobulin (IVIG) therapy is another treatment option.
A case who had no clinical finding except diffuse ecchymoses after traumatic delivery, but was considered to have NAIT due to severe thrombocytopenia and was successfully treated with platelet suspension and IVIG is presented. |
| first_indexed | 2024-03-12T20:40:26Z |
| format | Article |
| id | doaj.art-b1d4afa0969442e699373e1dd77a93e7 |
| institution | Directory Open Access Journal |
| issn | 2757-5241 |
| language | English |
| last_indexed | 2024-03-12T20:40:26Z |
| publishDate | 2021-08-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Forbes Tıp Dergisi |
| spelling | doaj.art-b1d4afa0969442e699373e1dd77a93e72023-08-01T10:47:26ZengGalenos YayineviForbes Tıp Dergisi2757-52412021-08-012213113510.5222/forbes.2021.14632FJM-14632Neonatal Alloimmune Thrombocytopenia Detected After Traumatic Delivery: Case ReportGökhan Kaya0Sema Tanriverdi1Celal Bayar University Faculty of Medicine, Department of Pediatrics, ManisaCelal Bayar University Faculty of Medicine, Department of Pediatrics, Department of Neonatalogy, ManisaNeonatal Alloimmune Thrombocytopenia (NAIT), a complication of maternal alloimmunization against fetal platelets, is the result of immune destruction of platelets due to maternal antibodies in the early period. The cause of thrombocytopenia here is by antibodies developed against human platelet antigens frequently inherited from the mother. The clinical manifestations of NAIT extend from asymptomatic to severe bleeding. Platelet suspension can be used in the setting of severe thrombocytopenia or life-threatening bleeding. High-dose intravenous immunoglobulin (IVIG) therapy is another treatment option. A case who had no clinical finding except diffuse ecchymoses after traumatic delivery, but was considered to have NAIT due to severe thrombocytopenia and was successfully treated with platelet suspension and IVIG is presented.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=forbes&un=FJM-14632immun thrombocytopeniaivigtraumatic deliverynewborn |
| spellingShingle | Gökhan Kaya Sema Tanriverdi Neonatal Alloimmune Thrombocytopenia Detected After Traumatic Delivery: Case Report Forbes Tıp Dergisi immun thrombocytopenia ivig traumatic delivery newborn |
| title | Neonatal Alloimmune Thrombocytopenia Detected After Traumatic Delivery: Case Report |
| title_full | Neonatal Alloimmune Thrombocytopenia Detected After Traumatic Delivery: Case Report |
| title_fullStr | Neonatal Alloimmune Thrombocytopenia Detected After Traumatic Delivery: Case Report |
| title_full_unstemmed | Neonatal Alloimmune Thrombocytopenia Detected After Traumatic Delivery: Case Report |
| title_short | Neonatal Alloimmune Thrombocytopenia Detected After Traumatic Delivery: Case Report |
| title_sort | neonatal alloimmune thrombocytopenia detected after traumatic delivery case report |
| topic | immun thrombocytopenia ivig traumatic delivery newborn |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=forbes&un=FJM-14632 |
| work_keys_str_mv | AT gokhankaya neonatalalloimmunethrombocytopeniadetectedaftertraumaticdeliverycasereport AT sematanriverdi neonatalalloimmunethrombocytopeniadetectedaftertraumaticdeliverycasereport |