IRF8: Mechanism of Action and Health Implications

IRF8: Mechanism of Action and Health Implications

Interferon regulatory factor 8 (IRF8) is a transcription factor of the IRF protein family. IRF8 was originally identified as an essentialfactor for myeloid cell lineage commitment and differentiation. Deletion of <i>Irf8</i> leads to massive accumulation of CD11b<sup>+</sup>G...

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Bibliographic Details
Main Authors: Hannah R. Moorman, Yazmin Reategui, Dakota B. Poschel, Kebin Liu
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
IRF8
myeloid cells
OPN
MDSCs
immunotherapy
Online Access:https://www.mdpi.com/2073-4409/11/17/2630

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