The long-term association of different dietary protein sources with metabolic syndrome
Abstract Due to scarce epidemiologic data linking dietary protein intakes and metabolic syndrome (MetS), we aim to determine the longitudinal association of different types of dietary protein with the incidence of MetS among Iranians adults. The study was conducted in the framework of the Isfahan Co...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2021-09-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-021-98688-0 |
| _version_ | 1818845928292876288 |
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| author | Parisa Hajihashemi Razieh Hassannejad Fahimeh Haghighatdoost Noushin Mohammadifard Masoumeh Sadeghi Hamidreza Roohafza Firoozeh Sajjadi Nizal Sarrafzadegan |
| author_facet | Parisa Hajihashemi Razieh Hassannejad Fahimeh Haghighatdoost Noushin Mohammadifard Masoumeh Sadeghi Hamidreza Roohafza Firoozeh Sajjadi Nizal Sarrafzadegan |
| author_sort | Parisa Hajihashemi |
| collection | DOAJ |
| description | Abstract Due to scarce epidemiologic data linking dietary protein intakes and metabolic syndrome (MetS), we aim to determine the longitudinal association of different types of dietary protein with the incidence of MetS among Iranians adults. The study was conducted in the framework of the Isfahan Cohort Study (ICS) on 6504 adults, aged ≥ 35 years, and free of MetS at baseline. A validated food frequency questionnaire was used for assessing usual dietary intakes. MetS was defined according to the Joint Scientific Statement. Mixed-effects logistic regression was applied to examine the associations between changes in weekly frequency consumption of protein and MetS status. After a median follow-up of 11.25 years, in multivariate-adjusted model, each additional frequency consumption of total protein intake (OR 0.83; 95% CI 0.81–0.85), animal protein (OR 0.80; 95% CI 0.77–0.83), plant protein (OR 0.70; 95% CI 0.64–0.76), red meat (OR 0.74; 95% CI 0.70–0.78), poultry (OR 0.73; 95% CI 0.68–0.78), egg (OR 0.79; 95% CI 0.72–0.88) and nuts and seeds (OR 0.77; 95% CI 0.71–0.84) was associated with reduced risk of MetS. No significant association was found for processed meat (OR 0.96; 95% CI 0.87–1.01) and legumes and soy (OR 0.96; 95% CI 0.86–1.07) with MetS. Our results suggest an independent inverse association between total protein, animal and plant protein and the risk of MetS. These associations did not differ by sex. Although our results can be considered to be a strategy to reduce MetS risk by dietary guidelines, randomized clinical trials are required to confirm our findings. |
| first_indexed | 2024-12-19T05:37:27Z |
| format | Article |
| id | doaj.art-b1ddce43cb634256a8a160753d72c402 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-19T05:37:27Z |
| publishDate | 2021-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-b1ddce43cb634256a8a160753d72c4022022-12-21T20:34:05ZengNature PortfolioScientific Reports2045-23222021-09-011111810.1038/s41598-021-98688-0The long-term association of different dietary protein sources with metabolic syndromeParisa Hajihashemi0Razieh Hassannejad1Fahimeh Haghighatdoost2Noushin Mohammadifard3Masoumeh Sadeghi4Hamidreza Roohafza5Firoozeh Sajjadi6Nizal Sarrafzadegan7Hypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical SciencesHeart Failure Research Center, Cardiovascular Research Institute, Isfahan University of Medical SciencesHypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical SciencesIsfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical SciencesCardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical SciencesInterventional Cardiology Research Center, Cardiovascular Research Institute, Isfahan University of Medical SciencesIsfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical SciencesIsfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical SciencesAbstract Due to scarce epidemiologic data linking dietary protein intakes and metabolic syndrome (MetS), we aim to determine the longitudinal association of different types of dietary protein with the incidence of MetS among Iranians adults. The study was conducted in the framework of the Isfahan Cohort Study (ICS) on 6504 adults, aged ≥ 35 years, and free of MetS at baseline. A validated food frequency questionnaire was used for assessing usual dietary intakes. MetS was defined according to the Joint Scientific Statement. Mixed-effects logistic regression was applied to examine the associations between changes in weekly frequency consumption of protein and MetS status. After a median follow-up of 11.25 years, in multivariate-adjusted model, each additional frequency consumption of total protein intake (OR 0.83; 95% CI 0.81–0.85), animal protein (OR 0.80; 95% CI 0.77–0.83), plant protein (OR 0.70; 95% CI 0.64–0.76), red meat (OR 0.74; 95% CI 0.70–0.78), poultry (OR 0.73; 95% CI 0.68–0.78), egg (OR 0.79; 95% CI 0.72–0.88) and nuts and seeds (OR 0.77; 95% CI 0.71–0.84) was associated with reduced risk of MetS. No significant association was found for processed meat (OR 0.96; 95% CI 0.87–1.01) and legumes and soy (OR 0.96; 95% CI 0.86–1.07) with MetS. Our results suggest an independent inverse association between total protein, animal and plant protein and the risk of MetS. These associations did not differ by sex. Although our results can be considered to be a strategy to reduce MetS risk by dietary guidelines, randomized clinical trials are required to confirm our findings.https://doi.org/10.1038/s41598-021-98688-0 |
| spellingShingle | Parisa Hajihashemi Razieh Hassannejad Fahimeh Haghighatdoost Noushin Mohammadifard Masoumeh Sadeghi Hamidreza Roohafza Firoozeh Sajjadi Nizal Sarrafzadegan The long-term association of different dietary protein sources with metabolic syndrome Scientific Reports |
| title | The long-term association of different dietary protein sources with metabolic syndrome |
| title_full | The long-term association of different dietary protein sources with metabolic syndrome |
| title_fullStr | The long-term association of different dietary protein sources with metabolic syndrome |
| title_full_unstemmed | The long-term association of different dietary protein sources with metabolic syndrome |
| title_short | The long-term association of different dietary protein sources with metabolic syndrome |
| title_sort | long term association of different dietary protein sources with metabolic syndrome |
| url | https://doi.org/10.1038/s41598-021-98688-0 |
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