Aquaporin 1 elicits cell motility and coordinates vascular bed formation by downregulating thrombospondin type‐1 domain‐containing 7A in glioblastoma

Aquaporin 1 elicits cell motility and coordinates vascular bed formation by downregulating thrombospondin type‐1 domain‐containing 7A in glioblastoma

Abstract Background Aquaporin (AQP) 1 expression has been linked with tumor malignancy but its role in glioblastoma (GBM), a lethal glioma, remains to be clarified. Methods AQP1 expression was examined in 33 human GBM specimens by immunohistochemistry. GBM cells (U251 and U87) that stably express AQ...

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Bibliographic Details
Main Authors: Masahiro Oishi, Seiichi Munesue, Ai Harashima, Mitsutoshi Nakada, Yasuhiko Yamamoto, Yasuhiko Hayashi
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Cancer Medicine
Subjects:
aquaporin‐1
glioblastoma
THSD7A
tube formation
vascular bed
Online Access:https://doi.org/10.1002/cam4.3032

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