Comparative Analysis of Endovascular Intervention and Endarterectomy in Patients with Femoral Artery Disease: A Systematic Review and Meta-Analysis
Peripheral artery disease is a prevalent illness affecting more than 200 million people worldwide. A commonly used technique to manage the condition has been open endarterectomy. However, in recent times, a shift towards minimally invasive techniques has resulted in endovascular intervention as a po...
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| Format: | Article |
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MDPI AG
2022-06-01
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| Series: | Hematology Reports |
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| Online Access: | https://www.mdpi.com/2038-8330/14/2/26 |
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| author | Nidhruv Ravikumar Gopika Sreejith Sharon Hiu Ching Law Prakhar Anand Noah Varghese Samrin Kagdi Navneet Kang Mohamed Nashnoush Sihat Salam Ibsen Ongidi |
| author_facet | Nidhruv Ravikumar Gopika Sreejith Sharon Hiu Ching Law Prakhar Anand Noah Varghese Samrin Kagdi Navneet Kang Mohamed Nashnoush Sihat Salam Ibsen Ongidi |
| author_sort | Nidhruv Ravikumar |
| collection | DOAJ |
| description | Peripheral artery disease is a prevalent illness affecting more than 200 million people worldwide. A commonly used technique to manage the condition has been open endarterectomy. However, in recent times, a shift towards minimally invasive techniques has resulted in endovascular intervention as a popular alternative. This review aims to assess the safety and efficacy of endovascular intervention when compared with endarterectomy. A systematic review of the articles published in PubMed, Ovid, Embase, and Scopus within the last 10 years was conducted. The PRISMA guidelines were adhered to, and the Newcastle-Ottawa and NICE quality assessment scales were used. A meta-analysis of proportions was performed using the RStudio software (RStudio Team (2021). RStudio: Integrated Development Environment for R, PBC, Boston, MA, USA). Twenty-six studies were included, with a total of 7126 patients (endovascular, 2496; endarterectomy, 4630). Technical success was greater for endarterectomy than endovascular intervention with an odds ratio of 0.38; 95% CI [0.27–0.54]. In terms of safety as well endovascular intervention was better than endarterectomy with an odds ratio of 0.22; 95% CI [0.15 to 0.31] for wound infection. Endovascular intervention is a safe and effective procedure; however, it cannot be considered superior to endarterectomy. |
| first_indexed | 2024-03-09T23:40:12Z |
| format | Article |
| id | doaj.art-b1e252f5acdb499fa865a253205bd73c |
| institution | Directory Open Access Journal |
| issn | 2038-8330 |
| language | English |
| last_indexed | 2024-03-09T23:40:12Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Hematology Reports |
| spelling | doaj.art-b1e252f5acdb499fa865a253205bd73c2023-11-23T16:54:05ZengMDPI AGHematology Reports2038-83302022-06-0114217920210.3390/hematolrep14020026Comparative Analysis of Endovascular Intervention and Endarterectomy in Patients with Femoral Artery Disease: A Systematic Review and Meta-AnalysisNidhruv Ravikumar0Gopika Sreejith1Sharon Hiu Ching Law2Prakhar Anand3Noah Varghese4Samrin Kagdi5Navneet Kang6Mohamed Nashnoush7Sihat Salam8Ibsen Ongidi9Department of Medicine, School of Medicine, Queen’s University Belfast, Belfast BT7 1NN, UKDepartment of Medicine, School of Medicine, Queen’s University Belfast, Belfast BT7 1NN, UKRadScholars Inc., Halifax, NS B3H 4R2, CanadaRadScholars Inc., Halifax, NS B3H 4R2, CanadaRadScholars Inc., Halifax, NS B3H 4R2, CanadaRadScholars Inc., Halifax, NS B3H 4R2, CanadaRadScholars Inc., Halifax, NS B3H 4R2, CanadaRadScholars Inc., Halifax, NS B3H 4R2, CanadaRadScholars Inc., Halifax, NS B3H 4R2, CanadaRadScholars Inc., Halifax, NS B3H 4R2, CanadaPeripheral artery disease is a prevalent illness affecting more than 200 million people worldwide. A commonly used technique to manage the condition has been open endarterectomy. However, in recent times, a shift towards minimally invasive techniques has resulted in endovascular intervention as a popular alternative. This review aims to assess the safety and efficacy of endovascular intervention when compared with endarterectomy. A systematic review of the articles published in PubMed, Ovid, Embase, and Scopus within the last 10 years was conducted. The PRISMA guidelines were adhered to, and the Newcastle-Ottawa and NICE quality assessment scales were used. A meta-analysis of proportions was performed using the RStudio software (RStudio Team (2021). RStudio: Integrated Development Environment for R, PBC, Boston, MA, USA). Twenty-six studies were included, with a total of 7126 patients (endovascular, 2496; endarterectomy, 4630). Technical success was greater for endarterectomy than endovascular intervention with an odds ratio of 0.38; 95% CI [0.27–0.54]. In terms of safety as well endovascular intervention was better than endarterectomy with an odds ratio of 0.22; 95% CI [0.15 to 0.31] for wound infection. Endovascular intervention is a safe and effective procedure; however, it cannot be considered superior to endarterectomy.https://www.mdpi.com/2038-8330/14/2/26endovascularendarterectomyfemoral arteryatherosclerosisminimally invasiveperipheral arterial disease |
| spellingShingle | Nidhruv Ravikumar Gopika Sreejith Sharon Hiu Ching Law Prakhar Anand Noah Varghese Samrin Kagdi Navneet Kang Mohamed Nashnoush Sihat Salam Ibsen Ongidi Comparative Analysis of Endovascular Intervention and Endarterectomy in Patients with Femoral Artery Disease: A Systematic Review and Meta-Analysis Hematology Reports endovascular endarterectomy femoral artery atherosclerosis minimally invasive peripheral arterial disease |
| title | Comparative Analysis of Endovascular Intervention and Endarterectomy in Patients with Femoral Artery Disease: A Systematic Review and Meta-Analysis |
| title_full | Comparative Analysis of Endovascular Intervention and Endarterectomy in Patients with Femoral Artery Disease: A Systematic Review and Meta-Analysis |
| title_fullStr | Comparative Analysis of Endovascular Intervention and Endarterectomy in Patients with Femoral Artery Disease: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | Comparative Analysis of Endovascular Intervention and Endarterectomy in Patients with Femoral Artery Disease: A Systematic Review and Meta-Analysis |
| title_short | Comparative Analysis of Endovascular Intervention and Endarterectomy in Patients with Femoral Artery Disease: A Systematic Review and Meta-Analysis |
| title_sort | comparative analysis of endovascular intervention and endarterectomy in patients with femoral artery disease a systematic review and meta analysis |
| topic | endovascular endarterectomy femoral artery atherosclerosis minimally invasive peripheral arterial disease |
| url | https://www.mdpi.com/2038-8330/14/2/26 |
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