Associations between stressful life events and diabetes: Findings from the China Kadoorie Biobank study of 500,000 adults
Abstract Aims/Introduction Evidence has shown that stressful life events are associated with the development of diabetes, yet studies in mainland China are scarce. In the present study, we explored the associations between cumulative and specific stressful life events and the prevalence of diabetes...
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| Formato: | Artigo |
| Idioma: | English |
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Wiley
2019-09-01
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| Colecção: | Journal of Diabetes Investigation |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1111/jdi.13028 |
| _version_ | 1831751416192958464 |
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| author | Meng Wang Wei‐Wei Gong Ru‐Ying Hu Jin Pan Jun Lv Yu Guo Zheng Bian Zheng‐Ming Chen Li‐Ming Li Jie‐Ming Zhong |
| author_facet | Meng Wang Wei‐Wei Gong Ru‐Ying Hu Jin Pan Jun Lv Yu Guo Zheng Bian Zheng‐Ming Chen Li‐Ming Li Jie‐Ming Zhong |
| author_sort | Meng Wang |
| collection | DOAJ |
| description | Abstract Aims/Introduction Evidence has shown that stressful life events are associated with the development of diabetes, yet studies in mainland China are scarce. In the present study, we explored the associations between cumulative and specific stressful life events and the prevalence of diabetes in Chinese adults. Materials and Methods The cross‐sectional data were from the China Kadoorie Biobank study, which enrolled approximately 500,000 adults aged 30–79 years from 10 diverse regions of China. Logistic regression models were used to calculate the adjusted odds ratio (OR) and the 95% confidence interval (CI). Results Of the 473,607 participants, 25,301 (5.34%) had type 2 diabetes (2.68% clinically‐identified and 2.66% screen‐detected). Participants who experienced one and two or more stressful life events were 1.10‐fold (OR 1.10, 95% CI 1.05–1.16) and 1.33‐fold (OR 1.33, 95% CI 1.13–1.57) more likely to have type 2 diabetes. Three categories of work‐related events (OR 1.15, 95% CI 1.01–1.31), as well as family‐related events (OR 1.11, 95% CI 1.06–1.18) and personal‐related events (OR 1.18, 95% CI 1.03–1.36), were associated with an increased likelihood of type 2 diabetes. Regarding the specific life events, the ORs of loss of job or retirement, as well as major conflict within family, death or major illness of other close family member and major injury or traffic accident, were 1.24 (95% CI 1.02–1.52), 1.24 (95% CI 1.08–1.43), 1.13 (95% CI 1.06–1.20) and 1.20 (95% CI 1.01–1.43), respectively. Conclusions The present study showed that cumulative and specific stressful life events were significantly associated with an increased prevalence of diabetes. |
| first_indexed | 2024-12-21T22:44:24Z |
| format | Article |
| id | doaj.art-b1e28f0d32e54e77a9e786b38e398889 |
| institution | Directory Open Access Journal |
| issn | 2040-1116 2040-1124 |
| language | English |
| last_indexed | 2024-12-21T22:44:24Z |
| publishDate | 2019-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Investigation |
| spelling | doaj.art-b1e28f0d32e54e77a9e786b38e3988892022-12-21T18:47:45ZengWileyJournal of Diabetes Investigation2040-11162040-11242019-09-011051215122210.1111/jdi.13028Associations between stressful life events and diabetes: Findings from the China Kadoorie Biobank study of 500,000 adultsMeng Wang0Wei‐Wei Gong1Ru‐Ying Hu2Jin Pan3Jun Lv4Yu Guo5Zheng Bian6Zheng‐Ming Chen7Li‐Ming Li8Jie‐Ming Zhong9Department of NCDs Control and Prevention Zhejiang Provincial Center for Disease Control and Prevention HangzhouChinaDepartment of NCDs Control and Prevention Zhejiang Provincial Center for Disease Control and Prevention HangzhouChinaDepartment of NCDs Control and Prevention Zhejiang Provincial Center for Disease Control and Prevention HangzhouChinaDepartment of NCDs Control and Prevention Zhejiang Provincial Center for Disease Control and Prevention HangzhouChinaDepartment of Epidemiology School of Public Health Peking University Health Science CenterBeijing ChinaChinese Academy of Medical Sciences Beijing ChinaChinese Academy of Medical Sciences Beijing ChinaClinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health University of Oxford Oxford UKDepartment of Epidemiology School of Public Health Peking University Health Science CenterBeijing ChinaDepartment of NCDs Control and Prevention Zhejiang Provincial Center for Disease Control and Prevention HangzhouChinaAbstract Aims/Introduction Evidence has shown that stressful life events are associated with the development of diabetes, yet studies in mainland China are scarce. In the present study, we explored the associations between cumulative and specific stressful life events and the prevalence of diabetes in Chinese adults. Materials and Methods The cross‐sectional data were from the China Kadoorie Biobank study, which enrolled approximately 500,000 adults aged 30–79 years from 10 diverse regions of China. Logistic regression models were used to calculate the adjusted odds ratio (OR) and the 95% confidence interval (CI). Results Of the 473,607 participants, 25,301 (5.34%) had type 2 diabetes (2.68% clinically‐identified and 2.66% screen‐detected). Participants who experienced one and two or more stressful life events were 1.10‐fold (OR 1.10, 95% CI 1.05–1.16) and 1.33‐fold (OR 1.33, 95% CI 1.13–1.57) more likely to have type 2 diabetes. Three categories of work‐related events (OR 1.15, 95% CI 1.01–1.31), as well as family‐related events (OR 1.11, 95% CI 1.06–1.18) and personal‐related events (OR 1.18, 95% CI 1.03–1.36), were associated with an increased likelihood of type 2 diabetes. Regarding the specific life events, the ORs of loss of job or retirement, as well as major conflict within family, death or major illness of other close family member and major injury or traffic accident, were 1.24 (95% CI 1.02–1.52), 1.24 (95% CI 1.08–1.43), 1.13 (95% CI 1.06–1.20) and 1.20 (95% CI 1.01–1.43), respectively. Conclusions The present study showed that cumulative and specific stressful life events were significantly associated with an increased prevalence of diabetes.https://doi.org/10.1111/jdi.13028DiabetesPrevalenceStressful life events |
| spellingShingle | Meng Wang Wei‐Wei Gong Ru‐Ying Hu Jin Pan Jun Lv Yu Guo Zheng Bian Zheng‐Ming Chen Li‐Ming Li Jie‐Ming Zhong Associations between stressful life events and diabetes: Findings from the China Kadoorie Biobank study of 500,000 adults Journal of Diabetes Investigation Diabetes Prevalence Stressful life events |
| title | Associations between stressful life events and diabetes: Findings from the China Kadoorie Biobank study of 500,000 adults |
| title_full | Associations between stressful life events and diabetes: Findings from the China Kadoorie Biobank study of 500,000 adults |
| title_fullStr | Associations between stressful life events and diabetes: Findings from the China Kadoorie Biobank study of 500,000 adults |
| title_full_unstemmed | Associations between stressful life events and diabetes: Findings from the China Kadoorie Biobank study of 500,000 adults |
| title_short | Associations between stressful life events and diabetes: Findings from the China Kadoorie Biobank study of 500,000 adults |
| title_sort | associations between stressful life events and diabetes findings from the china kadoorie biobank study of 500 000 adults |
| topic | Diabetes Prevalence Stressful life events |
| url | https://doi.org/10.1111/jdi.13028 |
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