Numerical solution of a malignant invasion model using some finite difference methods

In this article, one standard and four nonstandard finite difference methods are used to solve a cross-diffusion malignant invasion model. The model consists of a system of nonlinear coupled partial differential equations (PDEs) subject to specified initial and boundary conditions, and no exact solu...

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Main Authors: Appadu Appanah Rao, Waal Gysbert Nicolaas de
Format: Article
Language:English
Published: De Gruyter 2023-07-01
Series:Demonstratio Mathematica
Subjects:
Online Access:https://doi.org/10.1515/dema-2022-0244
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author Appadu Appanah Rao
Waal Gysbert Nicolaas de
author_facet Appadu Appanah Rao
Waal Gysbert Nicolaas de
author_sort Appadu Appanah Rao
collection DOAJ
description In this article, one standard and four nonstandard finite difference methods are used to solve a cross-diffusion malignant invasion model. The model consists of a system of nonlinear coupled partial differential equations (PDEs) subject to specified initial and boundary conditions, and no exact solution is known for this problem. It is difficult to obtain theoretically the stability region of the classical finite difference scheme to solve the set of nonlinear coupled PDEs, this is one of the challenges of this class of method in this work. Three nonstandard methods abbreviated as NSFD1, NSFD2, and NSFD3 are considered from the study of Chapwanya et al., and these methods have been constructed by the use of a more general function replacing the denominator of the discrete derivative and nonlocal approximations of nonlocal terms. It is shown that NSFD1, which preserves positivity when used to solve classical reaction-diffusion equations, does not inherit this property when used for the cross-diffusion system of PDEs. NSFD2 and NSFD3 are obtained by appropriate modifications of NSFD1. NSFD2 is positivity-preserving when the functional relationship [ψ(h)]2=2ϕ(k){\left[\psi \left(h)]}^{2}=2\phi \left(k) holds, while NSFD3 is unconditionally dynamically consistent with respect to positivity. First, we show that NSFD2 and NSFD3 are not consistent methods. Second, we tried to modify NSFD2 in order to make it consistent but we were not successful. Third, we extend NSFD3 so that it becomes consistent and still preserves positivity. We denote the extended version of NSFD3 as NSFD5. Finally, we compute the numerical rate of convergence in time for NSFD5 and show that it is close to the theoretical value. NSFD5 is consistent under certain conditions on the step sizes and is unconditionally positivity-preserving.
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spelling doaj.art-b1e67582808c4807a1ad2722fc59012f2023-08-01T05:14:47ZengDe GruyterDemonstratio Mathematica2391-46612023-07-015613893310.1515/dema-2022-0244Numerical solution of a malignant invasion model using some finite difference methodsAppadu Appanah Rao0Waal Gysbert Nicolaas de1Department of Mathematics and Applied Mathematics, Nelson Mandela University, University Way, Summerstrand, Gqeberha, South AfricaDepartment of Mathematics and Applied Mathematics, Nelson Mandela University, University Way, Summerstrand, Gqeberha, South AfricaIn this article, one standard and four nonstandard finite difference methods are used to solve a cross-diffusion malignant invasion model. The model consists of a system of nonlinear coupled partial differential equations (PDEs) subject to specified initial and boundary conditions, and no exact solution is known for this problem. It is difficult to obtain theoretically the stability region of the classical finite difference scheme to solve the set of nonlinear coupled PDEs, this is one of the challenges of this class of method in this work. Three nonstandard methods abbreviated as NSFD1, NSFD2, and NSFD3 are considered from the study of Chapwanya et al., and these methods have been constructed by the use of a more general function replacing the denominator of the discrete derivative and nonlocal approximations of nonlocal terms. It is shown that NSFD1, which preserves positivity when used to solve classical reaction-diffusion equations, does not inherit this property when used for the cross-diffusion system of PDEs. NSFD2 and NSFD3 are obtained by appropriate modifications of NSFD1. NSFD2 is positivity-preserving when the functional relationship [ψ(h)]2=2ϕ(k){\left[\psi \left(h)]}^{2}=2\phi \left(k) holds, while NSFD3 is unconditionally dynamically consistent with respect to positivity. First, we show that NSFD2 and NSFD3 are not consistent methods. Second, we tried to modify NSFD2 in order to make it consistent but we were not successful. Third, we extend NSFD3 so that it becomes consistent and still preserves positivity. We denote the extended version of NSFD3 as NSFD5. Finally, we compute the numerical rate of convergence in time for NSFD5 and show that it is close to the theoretical value. NSFD5 is consistent under certain conditions on the step sizes and is unconditionally positivity-preserving.https://doi.org/10.1515/dema-2022-0244standard finite difference methodnonstandard finite difference methodconsistencypositivity preservingcross-diffusion35k5565m0692-10
spellingShingle Appadu Appanah Rao
Waal Gysbert Nicolaas de
Numerical solution of a malignant invasion model using some finite difference methods
Demonstratio Mathematica
standard finite difference method
nonstandard finite difference method
consistency
positivity preserving
cross-diffusion
35k55
65m06
92-10
title Numerical solution of a malignant invasion model using some finite difference methods
title_full Numerical solution of a malignant invasion model using some finite difference methods
title_fullStr Numerical solution of a malignant invasion model using some finite difference methods
title_full_unstemmed Numerical solution of a malignant invasion model using some finite difference methods
title_short Numerical solution of a malignant invasion model using some finite difference methods
title_sort numerical solution of a malignant invasion model using some finite difference methods
topic standard finite difference method
nonstandard finite difference method
consistency
positivity preserving
cross-diffusion
35k55
65m06
92-10
url https://doi.org/10.1515/dema-2022-0244
work_keys_str_mv AT appaduappanahrao numericalsolutionofamalignantinvasionmodelusingsomefinitedifferencemethods
AT waalgysbertnicolaasde numericalsolutionofamalignantinvasionmodelusingsomefinitedifferencemethods