Effects of physical exercise associated with a diet enriched with natural antioxidants on cerebral hypoperfusion and reperfusion injury in spontaneously hypertensive rats

Effects of physical exercise associated with a diet enriched with natural antioxidants on cerebral hypoperfusion and reperfusion injury in spontaneously hypertensive rats

Oxidative stress is implicated in the pathogenesis of arterial hypertension. The reduction in the bioavailability of nitric oxide (NO) causes endothelial dysfunction, altering the functions of cerebral blood vessels. Physical exercise and intake of antioxidants improve the redox state, increasing th...

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Bibliographic Details
Main Authors: Dominga Lapi, Giuseppe Federighi, Maria Serena Lonardo, Martina Chiurazzi, Espedita Muscariello, Giancarlo Tenore, Antonio Colantuoni, Ettore Novellino, Rossana Scuri
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Physiology
Subjects:
hypertension
hypoperfusion
physical exercise
pial microcirculation
polyphenols
reperfusion
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1091889/full

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