DropSOAC: Stabilizing Microfluidic Drops for Time-Lapse Quantification of Single-Cell Bacterial Physiology

DropSOAC: Stabilizing Microfluidic Drops for Time-Lapse Quantification of Single-Cell Bacterial Physiology

The physiological heterogeneity of cells within a microbial population imparts resilience to stresses such as antimicrobial treatments and nutrient limitation. This resilience is partially due to a subpopulation of cells that can survive such stresses and regenerate the community. Microfluidic appro...

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Bibliographic Details
Main Authors: Shawna L. Pratt, Geoffrey K. Zath, Tatsuya Akiyama, Kerry S. Williamson, Michael J. Franklin, Connie B. Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Microbiology
Subjects:
drop-based microfluidics
single cell
growth rate
lag time
time-lapse imaging
biofilm
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02112/full

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