Large-scale fully printed “Lego Bricks” type wearable sweat sensor for physical activity monitoring

Abstract Wearable sweat sensors are becoming increasingly popular for their robust capabilities in non-invasive, dynamic, and continuous real-time monitoring of biological information. Real-time monitoring of large-scale samples is crucial for realizing intelligent health. A major bottleneck for ena...

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Main Authors: Wenhui Ji, Huanzhuan Liu, Yadong Liu, Wei Zhang, Tong Zhou, Xinxin Liu, Chao Tao, Jiangxuan Dai, Baoli Zha, Ruijie Xie, Jiansheng Wu, Qiong Wu, Weina Zhang, Lin Li, Fengwei Huo
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:npj Flexible Electronics
Online Access:https://doi.org/10.1038/s41528-023-00285-w
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author Wenhui Ji
Huanzhuan Liu
Yadong Liu
Wei Zhang
Tong Zhou
Xinxin Liu
Chao Tao
Jiangxuan Dai
Baoli Zha
Ruijie Xie
Jiansheng Wu
Qiong Wu
Weina Zhang
Lin Li
Fengwei Huo
author_facet Wenhui Ji
Huanzhuan Liu
Yadong Liu
Wei Zhang
Tong Zhou
Xinxin Liu
Chao Tao
Jiangxuan Dai
Baoli Zha
Ruijie Xie
Jiansheng Wu
Qiong Wu
Weina Zhang
Lin Li
Fengwei Huo
author_sort Wenhui Ji
collection DOAJ
description Abstract Wearable sweat sensors are becoming increasingly popular for their robust capabilities in non-invasive, dynamic, and continuous real-time monitoring of biological information. Real-time monitoring of large-scale samples is crucial for realizing intelligent health. A major bottleneck for enabling large-scale sweat elucidation is the fabrication of wearable sensors equipped with microfluidic devices and flexible electrodes in a cost-effective, homogeneous performance and rapid large-scale way. Herein, a “Screen+Wax”-printing technique was introduced to prepare these components and construct “Lego Bricks” type wearable sweat sensor sensor to monitor sweat Na+ and K+. Flexible electrode arrays and paper-based microfluidic layers (they act as building blocks) were fabricated on polyethylene terephthalate and paper surfaces, respectively, using screen printing and wax printing. Gold nanoparticles and Na+/K+ ion-selective membranes were modified on the electrode surfaces by electrodeposition and drop coating, respectively. In this work, we highlight the excellent performance of the “Lego Bricks” type wearable sweat sensor in testing the Na+ and K+ imbalance of sweat from different body regions during exercise and, more significantly, to track the physical activity during prolonged exercise under different interventions. Furthermore, the prepared “Lego Bricks” wearable sweat ion electrochemical sensor is demonstrated to be capable of large-scale samples elucidation with outstanding performance and cost-effectiveness, which is expected to deeply integrate sweat monitoring into physical activity, providing an important tool for intelligent health.
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spelling doaj.art-b1f81e1768ae4706b511c4f05772d27f2023-12-24T12:32:07ZengNature Portfolionpj Flexible Electronics2397-46212023-12-017111210.1038/s41528-023-00285-wLarge-scale fully printed “Lego Bricks” type wearable sweat sensor for physical activity monitoringWenhui Ji0Huanzhuan Liu1Yadong Liu2Wei Zhang3Tong Zhou4Xinxin Liu5Chao Tao6Jiangxuan Dai7Baoli Zha8Ruijie Xie9Jiansheng Wu10Qiong Wu11Weina Zhang12Lin Li13Fengwei Huo14Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University (Nanjing Tech)Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University (Nanjing Tech)Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University (Nanjing Tech)Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University (Nanjing Tech)Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University (Nanjing Tech)Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University (Nanjing Tech)Department of Neurosurgery, The First Affiliated Hospital of Nanjing Medical UniversityThe Institute of Flexible Electronics (IFE, Future Technologies), Xiamen UniversityKey Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University (Nanjing Tech)The Institute of Flexible Electronics (IFE, Future Technologies), Xiamen UniversityKey Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University (Nanjing Tech)Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University (Nanjing Tech)Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University (Nanjing Tech)Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University (Nanjing Tech)Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University (Nanjing Tech)Abstract Wearable sweat sensors are becoming increasingly popular for their robust capabilities in non-invasive, dynamic, and continuous real-time monitoring of biological information. Real-time monitoring of large-scale samples is crucial for realizing intelligent health. A major bottleneck for enabling large-scale sweat elucidation is the fabrication of wearable sensors equipped with microfluidic devices and flexible electrodes in a cost-effective, homogeneous performance and rapid large-scale way. Herein, a “Screen+Wax”-printing technique was introduced to prepare these components and construct “Lego Bricks” type wearable sweat sensor sensor to monitor sweat Na+ and K+. Flexible electrode arrays and paper-based microfluidic layers (they act as building blocks) were fabricated on polyethylene terephthalate and paper surfaces, respectively, using screen printing and wax printing. Gold nanoparticles and Na+/K+ ion-selective membranes were modified on the electrode surfaces by electrodeposition and drop coating, respectively. In this work, we highlight the excellent performance of the “Lego Bricks” type wearable sweat sensor in testing the Na+ and K+ imbalance of sweat from different body regions during exercise and, more significantly, to track the physical activity during prolonged exercise under different interventions. Furthermore, the prepared “Lego Bricks” wearable sweat ion electrochemical sensor is demonstrated to be capable of large-scale samples elucidation with outstanding performance and cost-effectiveness, which is expected to deeply integrate sweat monitoring into physical activity, providing an important tool for intelligent health.https://doi.org/10.1038/s41528-023-00285-w
spellingShingle Wenhui Ji
Huanzhuan Liu
Yadong Liu
Wei Zhang
Tong Zhou
Xinxin Liu
Chao Tao
Jiangxuan Dai
Baoli Zha
Ruijie Xie
Jiansheng Wu
Qiong Wu
Weina Zhang
Lin Li
Fengwei Huo
Large-scale fully printed “Lego Bricks” type wearable sweat sensor for physical activity monitoring
npj Flexible Electronics
title Large-scale fully printed “Lego Bricks” type wearable sweat sensor for physical activity monitoring
title_full Large-scale fully printed “Lego Bricks” type wearable sweat sensor for physical activity monitoring
title_fullStr Large-scale fully printed “Lego Bricks” type wearable sweat sensor for physical activity monitoring
title_full_unstemmed Large-scale fully printed “Lego Bricks” type wearable sweat sensor for physical activity monitoring
title_short Large-scale fully printed “Lego Bricks” type wearable sweat sensor for physical activity monitoring
title_sort large scale fully printed lego bricks type wearable sweat sensor for physical activity monitoring
url https://doi.org/10.1038/s41528-023-00285-w
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