Toxic thyroid adenoma with hypercalcemia mimicking an intra-thyroidal parathyroid adenoma
Hypercalcemia is a clinical condition characterized by elevated circulating serum calcium levels either due to raised parathyroid hormone in hyperparathyroidism or due to secondary causes of hypercalcemia without elevated parathyroid hormone levels. However, hyperthyroidism may occasionally present...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2022-01-01
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| Series: | Asia Oceania Journal of Nuclear Medicine and Biology |
| Subjects: | |
| Online Access: | https://aojnmb.mums.ac.ir/article_18932_b0d476716e889d923087acc0b9460644.pdf |
| _version_ | 1831808650087235584 |
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| author | Venkata Subramanian Krishnaraju Ritesh Upadhyay Ashwani Sood Anish Bhattacharya Bhagwant Mittal |
| author_facet | Venkata Subramanian Krishnaraju Ritesh Upadhyay Ashwani Sood Anish Bhattacharya Bhagwant Mittal |
| author_sort | Venkata Subramanian Krishnaraju |
| collection | DOAJ |
| description | Hypercalcemia is a clinical condition characterized by elevated circulating serum calcium levels either due to raised parathyroid hormone in hyperparathyroidism or due to secondary causes of hypercalcemia without elevated parathyroid hormone levels. However, hyperthyroidism may occasionally present with incidentally detected hypercalcemia. We present a case of a 53-year-old woman with a previous history of an underlying thyroid disorder, now presented with features of hypercalcemia and mildly elevated parathyroid hormone levels. Her ultrasonography of the neck was suggestive of an intra-thyroidal parathyroid adenoma and it was localized as a tracer avid lesion within the thyroid gland on dual-phase 99mTc-sestamibi planar scintigraphy with single photon emission computed tomography/ computed tomography (SPECT/CT). However, a subsequent thyroid profile followed by 99mTc- pertechnetate thyroid scintigraphy showed a hot nodule in the thyroid gland which changed the diagnosis to a toxic thyroid adenoma. She was treated with radioactive iodine ablation and thyrotoxicosis resolved and the serum calcium levels normalized on her follow-up. |
| first_indexed | 2024-12-22T20:27:11Z |
| format | Article |
| id | doaj.art-b200c119e94e45359ffb5ddfd51f9693 |
| institution | Directory Open Access Journal |
| issn | 2322-5718 2322-5726 |
| language | English |
| last_indexed | 2024-12-22T20:27:11Z |
| publishDate | 2022-01-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Asia Oceania Journal of Nuclear Medicine and Biology |
| spelling | doaj.art-b200c119e94e45359ffb5ddfd51f96932022-12-21T18:13:42ZengMashhad University of Medical SciencesAsia Oceania Journal of Nuclear Medicine and Biology2322-57182322-57262022-01-01101535610.22038/aojnmb.2021.57103.139818932Toxic thyroid adenoma with hypercalcemia mimicking an intra-thyroidal parathyroid adenomaVenkata Subramanian Krishnaraju0Ritesh Upadhyay1Ashwani Sood2Anish Bhattacharya3Bhagwant Mittal4Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaDepartment of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaDepartment of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaDepartment of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaDepartment of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaHypercalcemia is a clinical condition characterized by elevated circulating serum calcium levels either due to raised parathyroid hormone in hyperparathyroidism or due to secondary causes of hypercalcemia without elevated parathyroid hormone levels. However, hyperthyroidism may occasionally present with incidentally detected hypercalcemia. We present a case of a 53-year-old woman with a previous history of an underlying thyroid disorder, now presented with features of hypercalcemia and mildly elevated parathyroid hormone levels. Her ultrasonography of the neck was suggestive of an intra-thyroidal parathyroid adenoma and it was localized as a tracer avid lesion within the thyroid gland on dual-phase 99mTc-sestamibi planar scintigraphy with single photon emission computed tomography/ computed tomography (SPECT/CT). However, a subsequent thyroid profile followed by 99mTc- pertechnetate thyroid scintigraphy showed a hot nodule in the thyroid gland which changed the diagnosis to a toxic thyroid adenoma. She was treated with radioactive iodine ablation and thyrotoxicosis resolved and the serum calcium levels normalized on her follow-up.https://aojnmb.mums.ac.ir/article_18932_b0d476716e889d923087acc0b9460644.pdfthyroid adenoma hypercalcemiaparathyroid adenomasestamibipertechnetate |
| spellingShingle | Venkata Subramanian Krishnaraju Ritesh Upadhyay Ashwani Sood Anish Bhattacharya Bhagwant Mittal Toxic thyroid adenoma with hypercalcemia mimicking an intra-thyroidal parathyroid adenoma Asia Oceania Journal of Nuclear Medicine and Biology thyroid adenoma hypercalcemia parathyroid adenoma sestamibi pertechnetate |
| title | Toxic thyroid adenoma with hypercalcemia mimicking an intra-thyroidal parathyroid adenoma |
| title_full | Toxic thyroid adenoma with hypercalcemia mimicking an intra-thyroidal parathyroid adenoma |
| title_fullStr | Toxic thyroid adenoma with hypercalcemia mimicking an intra-thyroidal parathyroid adenoma |
| title_full_unstemmed | Toxic thyroid adenoma with hypercalcemia mimicking an intra-thyroidal parathyroid adenoma |
| title_short | Toxic thyroid adenoma with hypercalcemia mimicking an intra-thyroidal parathyroid adenoma |
| title_sort | toxic thyroid adenoma with hypercalcemia mimicking an intra thyroidal parathyroid adenoma |
| topic | thyroid adenoma hypercalcemia parathyroid adenoma sestamibi pertechnetate |
| url | https://aojnmb.mums.ac.ir/article_18932_b0d476716e889d923087acc0b9460644.pdf |
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