Knockout of <i>stim2a</i> Increases Calcium Oscillations in Neurons and Induces Hyperactive-Like Phenotype in Zebrafish Larvae

Knockout of <i>stim2a</i> Increases Calcium Oscillations in Neurons and Induces Hyperactive-Like Phenotype in Zebrafish Larvae

Stromal interaction molecule (STIM) proteins play a crucial role in store-operated calcium entry (SOCE) as endoplasmic reticulum Ca<sup>2+</sup> sensors. In neurons, STIM2 was shown to have distinct functions from STIM1. However, its role in brain activity and behavior was not fully eluc...

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Bibliographic Details
Main Authors: Rishikesh Kumar Gupta, Iga Wasilewska, Oksana Palchevska, Jacek Kuźnicki
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
SOCE
Stim2a
calcium toolkit
zebrafish
behavioral tests
hyperactivity
Online Access:https://www.mdpi.com/1422-0067/21/17/6198

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