Cytological features of ossifying fibromyxoid tumor of soft parts

A case of ossifying fibromyxoid tumor (OFMT) evaluated during an intraoperative pathological consultation is presented. The patient, a 70-year-old woman was being followed because of a tumor in the left buttock. Cytological smears were obtained after scrapping the tumoral cut surface and revealed a...

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Main Authors: F Álvarez-Rodríguez, J A Jiménez-Heffernan, C Salas, M Pastrana, E Sanz
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2012-01-01
Series:Journal of Cytology
Subjects:
Online Access:http://www.jcytol.org/article.asp?issn=0970-9371;year=2012;volume=29;issue=3;spage=205;epage=207;aulast=Álvarez-Rodríguez
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author F Álvarez-Rodríguez
J A Jiménez-Heffernan
C Salas
M Pastrana
E Sanz
author_facet F Álvarez-Rodríguez
J A Jiménez-Heffernan
C Salas
M Pastrana
E Sanz
author_sort F Álvarez-Rodríguez
collection DOAJ
description A case of ossifying fibromyxoid tumor (OFMT) evaluated during an intraoperative pathological consultation is presented. The patient, a 70-year-old woman was being followed because of a tumor in the left buttock. Cytological smears were obtained after scrapping the tumoral cut surface and revealed a myxoid background with fragments composed of a denser, fibrillar metachromatic stroma with accompanying round to oval tumoral nuclei and no vessels. Single cells were predominantly monomorphic with a round to oval morphology and scarce cytoplasm. The most relevant feature of the tumor was its peripheral, plaque-like, calcified consistency. The review of the cytological descriptions of four cases revealed similar findings that can be presumed as those of a low-grade myxoid tumor of round to oval cells. A specific recognition of OFMT based solely on cytological features seems difficult. However, when such features are coupled with characteristic radiological findings (peripheral calcification) this entity must be considered.
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spelling doaj.art-b20808f6b7154a44b6c01ce55aee805c2022-12-21T21:43:13ZengWolters Kluwer Medknow PublicationsJournal of Cytology0970-93712012-01-0129320520710.4103/0970-9371.101180Cytological features of ossifying fibromyxoid tumor of soft partsF Álvarez-RodríguezJ A Jiménez-HeffernanC SalasM PastranaE SanzA case of ossifying fibromyxoid tumor (OFMT) evaluated during an intraoperative pathological consultation is presented. The patient, a 70-year-old woman was being followed because of a tumor in the left buttock. Cytological smears were obtained after scrapping the tumoral cut surface and revealed a myxoid background with fragments composed of a denser, fibrillar metachromatic stroma with accompanying round to oval tumoral nuclei and no vessels. Single cells were predominantly monomorphic with a round to oval morphology and scarce cytoplasm. The most relevant feature of the tumor was its peripheral, plaque-like, calcified consistency. The review of the cytological descriptions of four cases revealed similar findings that can be presumed as those of a low-grade myxoid tumor of round to oval cells. A specific recognition of OFMT based solely on cytological features seems difficult. However, when such features are coupled with characteristic radiological findings (peripheral calcification) this entity must be considered.http://www.jcytol.org/article.asp?issn=0970-9371;year=2012;volume=29;issue=3;spage=205;epage=207;aulast=Álvarez-RodríguezCytology; ossifying fibromyxoid tumor; soft tissue tumors
spellingShingle F Álvarez-Rodríguez
J A Jiménez-Heffernan
C Salas
M Pastrana
E Sanz
Cytological features of ossifying fibromyxoid tumor of soft parts
Journal of Cytology
Cytology; ossifying fibromyxoid tumor; soft tissue tumors
title Cytological features of ossifying fibromyxoid tumor of soft parts
title_full Cytological features of ossifying fibromyxoid tumor of soft parts
title_fullStr Cytological features of ossifying fibromyxoid tumor of soft parts
title_full_unstemmed Cytological features of ossifying fibromyxoid tumor of soft parts
title_short Cytological features of ossifying fibromyxoid tumor of soft parts
title_sort cytological features of ossifying fibromyxoid tumor of soft parts
topic Cytology; ossifying fibromyxoid tumor; soft tissue tumors
url http://www.jcytol.org/article.asp?issn=0970-9371;year=2012;volume=29;issue=3;spage=205;epage=207;aulast=Álvarez-Rodríguez
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