Synthesis and evaluation of chitosan based controlled release nanoparticles for the delivery of ticagrelor

Synthesis and evaluation of chitosan based controlled release nanoparticles for the delivery of ticagrelor

The aim of this contemporary work was to formulate a controlled release mucoadhesive nanoparticle formulation for enhancing the oral bioavailability of Ticagrelor (TG), a BCS class IV drug, having low oral bioavailability of about 36%. The nanoparticles can act as efficient carriers for hydrophobic...

Full description

Bibliographic Details
Main Authors: Nariman Shahid, Alia Erum, Muhammad Zaman, Ume Ruqia Tulain, Qurat-ul-ain Shoaib, Nadia Shamshad Malik, Rizwana Kausar, Ayesha Rashid, Umaira Rehman
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Designed Monomers and Polymers
Subjects:
nanoparticles
chitosan
ticagrelor
hydrophobic
hydrophilic
ionic gelation
bioavailability
Online Access:http://dx.doi.org/10.1080/15685551.2022.2054117

Similar Items

Similar Items