Cyclic AMP-response element regulated cell cycle arrests in cancer cells.
Recently, we have demonstrated that trichosanthin (TCS), a promising agent for the treatment of cervical adenocarcinoma, inhibited HeLa cell proliferation through the PKC/MAPK/CREB signal pathway. Furthermore, TCS down-regulated Bcl-2 expression was abrogated by a decoy oligonucleotide (OGN) to the...
Main Authors: | Ping Wang, Shuaishuai Huang, Feng Wang, Yu Ren, Michael Hehir, Xue Wang, Jie Cai |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3696002?pdf=render |
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