Optimizing clinical dosing of combination broadly neutralizing antibodies for HIV prevention.

Broadly neutralizing antibodies (bNAbs) are promising agents to prevent HIV infection and achieve HIV remission without antiretroviral therapy (ART). As with ART, bNAb combinations are likely needed to cover HIV's extensive diversity. Not all bNAbs are identical in terms of their breadth, poten...

Full description

Bibliographic Details
Main Authors: Bryan T Mayer, Allan C deCamp, Yunda Huang, Joshua T Schiffer, Raphael Gottardo, Peter B Gilbert, Daniel B Reeves
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-04-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010003