The unmet need for pertussis prevention in patients with chronic obstructive pulmonary disease in the Italian context
Despite high rates of vaccination, pertussis resurgence has been reported worldwide in recent years, including in Italy, especially in older adults. Chronic obstructive pulmonary disease (COPD) is a respiratory disease associated with progressive inflammation of the respiratory tract. Regional popul...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2020-02-01
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| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/21645515.2019.1652517 |
| _version_ | 1797677365262811136 |
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| author | Francesco Blasi Paolo Bonanni Fulvio Braido Giovanni Gabutti Federico Marchetti Stefano Centanni |
| author_facet | Francesco Blasi Paolo Bonanni Fulvio Braido Giovanni Gabutti Federico Marchetti Stefano Centanni |
| author_sort | Francesco Blasi |
| collection | DOAJ |
| description | Despite high rates of vaccination, pertussis resurgence has been reported worldwide in recent years, including in Italy, especially in older adults. Chronic obstructive pulmonary disease (COPD) is a respiratory disease associated with progressive inflammation of the respiratory tract. Regional population studies have shown the prevalence of COPD in Italy to be approximately 15% with an age-dependent increase in proportion of COPD cases. Emerging data shows that individuals with COPD are at high risk of contracting pertussis. Furthermore, those who develop pertussis could experience exacerbation of their pre-existent COPD and further susceptibility to other infections. Immunization programs in Italy currently recommend a decennial reduced-antigen-content diphtheria-tetanus-acellular pertussis booster vaccine dose for adults. Active measures to encourage booster vaccination, especially for high-risk adults such as those with COPD, could positively impact pertussis morbidity and the associated healthcare burden. |
| first_indexed | 2024-03-11T22:44:00Z |
| format | Article |
| id | doaj.art-b20ec411801a4a1c869707d359dede4a |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T22:44:00Z |
| publishDate | 2020-02-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-b20ec411801a4a1c869707d359dede4a2023-09-22T08:45:33ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2020-02-0116234034810.1080/21645515.2019.16525171652517The unmet need for pertussis prevention in patients with chronic obstructive pulmonary disease in the Italian contextFrancesco Blasi0Paolo Bonanni1Fulvio Braido2Giovanni Gabutti3Federico Marchetti4Stefano Centanni5University of MilanUniversity of FlorenceIRCCS Ospedale Policlinico San MartinoUniversity of FerraraGSKUniversity of MilanDespite high rates of vaccination, pertussis resurgence has been reported worldwide in recent years, including in Italy, especially in older adults. Chronic obstructive pulmonary disease (COPD) is a respiratory disease associated with progressive inflammation of the respiratory tract. Regional population studies have shown the prevalence of COPD in Italy to be approximately 15% with an age-dependent increase in proportion of COPD cases. Emerging data shows that individuals with COPD are at high risk of contracting pertussis. Furthermore, those who develop pertussis could experience exacerbation of their pre-existent COPD and further susceptibility to other infections. Immunization programs in Italy currently recommend a decennial reduced-antigen-content diphtheria-tetanus-acellular pertussis booster vaccine dose for adults. Active measures to encourage booster vaccination, especially for high-risk adults such as those with COPD, could positively impact pertussis morbidity and the associated healthcare burden.http://dx.doi.org/10.1080/21645515.2019.1652517copdpertussiswhooping coughitalyvaccinationtdap vaccine |
| spellingShingle | Francesco Blasi Paolo Bonanni Fulvio Braido Giovanni Gabutti Federico Marchetti Stefano Centanni The unmet need for pertussis prevention in patients with chronic obstructive pulmonary disease in the Italian context Human Vaccines & Immunotherapeutics copd pertussis whooping cough italy vaccination tdap vaccine |
| title | The unmet need for pertussis prevention in patients with chronic obstructive pulmonary disease in the Italian context |
| title_full | The unmet need for pertussis prevention in patients with chronic obstructive pulmonary disease in the Italian context |
| title_fullStr | The unmet need for pertussis prevention in patients with chronic obstructive pulmonary disease in the Italian context |
| title_full_unstemmed | The unmet need for pertussis prevention in patients with chronic obstructive pulmonary disease in the Italian context |
| title_short | The unmet need for pertussis prevention in patients with chronic obstructive pulmonary disease in the Italian context |
| title_sort | unmet need for pertussis prevention in patients with chronic obstructive pulmonary disease in the italian context |
| topic | copd pertussis whooping cough italy vaccination tdap vaccine |
| url | http://dx.doi.org/10.1080/21645515.2019.1652517 |
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