SARS-CoV-2 infection severity and mortality is modulated by repeat-mediated regulation of alternative splicing

SARS-CoV-2 infection severity and mortality is modulated by repeat-mediated regulation of alternative splicing

ABSTRACT Like single-stranded RNA viruses, SARS-CoV-2 hijacks the host transcriptional machinery for its own replication. Numerous traditional differential gene expression-based investigations have examined the diverse clinical symptoms caused by SARS-CoV-2 infection. The virus, on the other hand, a...

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Bibliographic Details
Main Authors: Priyanka Mehta, Partha Chattopadhyay, Varsha Ravi, Bansidhar Tarai, Sandeep Budhiraja, Rajesh Pandey
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:Microbiology Spectrum
Subjects:
COVID-19
differential transcript expression
alternative splicing
alternate promoter usage
repeat elements
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01351-23

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